Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients

Table 3 Escherichia coli non-susceptibility rates ^a for cases with available clinical data

Antimicrobial agent	AUC (n = 119)	TotalE. coli cases with available clinical info (n = 214)
Amoxicillin	26.1	27.6
Amoxicillin/clavulanic acid	5.0	4.7
Cefalothin	6.7	7.9
Cefuroxime sodium^b	0.8	1.4
Cefuroxime axetil^c	2.5	3.3
Co-trimoxazole	18.5	18.7
Nalidixic acid	5.0	7.9
Ciprofloxacin	1.7	4.2
Mecillinam	2.5	2.8
Nitrofurantoin	7.6	7.0
Fosfomycin ^d	0	0.5
Cefotaxime	0.8	2.3
Ceftazidime	0	0
Gentamicin	0	1.4
Netilimicin	0	0.5
Amikacin	0	0
Piperacillin-tazobactam	0	0
Ticarcillin-clavulanate	0.8	0.9
Imipenem	0	0
Cefditoren	1.7	1.9

AUC. acute uncomplicated cystitis; ^a CLSI 2011 breakpoints of susceptibility were applied; ^bResults reported according to the breakpoint of parenteral cefuroxime; ^c Results reported according to the breakpoint of oral cefuroxime; ^d Fosfomycin trometamol is no long marketed in Greece.

ISSN: 1471-2334