Discrepancy between effects of carbapenems and flomoxef in treating nosocomial hemodialysis access-related bacteremia secondary to extended spectrum beta-lactamase producing klebsiella pneumoniaein patients on maintenance hemodialysis

Table 2 Comparisons of demographic and clinical data between the deceased and survived groups of the 42 patients with CRB; Variables with a p -value < 0.1 by univariate analysis were subjected to multivariate analysis

Variable	Survived group	Deceased group	P	Total
Variable	n = 15	n = 27	P	n = 42
Mean age, years	63.2 ± 7.6	65.7 ± 10.3	NS	64.8 ± 10.0
Male (%)	12/15 (80)	21/27 (77.8)	NS	33/42 (78.6)
Patients aged >65 years (%)	8/15 (53.3)	16/27 (59.3)	NS	24/42 (57.1)
Flomoxef treatment (%) ^a	3 (20)	16 (59.3)	0.009	19 (45.2)
Treatment within 5 days	9 (60)	6 (22.2)	0.021	15 (35.7)
Pitt bacteremia score, mean ± SD ^a	4.27 ± 1.03	5.85 ± 1.7	0.002	5.29 ± 1.67
Serum albumin(g/dL), mean ± SD	2.70 ± 0.31	2.12 ± 0.42	0.046	2.33 ± 0.61
Hemoglobin(g/dL), mean ± SD	8.98 ± 0.71	9.13 ± 1.92	NS	9.08 ± 1.56
Hospital days before onset, mean ± SD	49 ± 35.8	116.9 ± 87.5	0.039	92.6 ± 79.6
No. of hospital days before onset > 30 (%)	8/15 (53.3)	23 (85.2)	0.034	30/42 (71.4)
Duration of catheter-dependent HD(days)	24.5 ± 9.2	43.6 ± 12.3	0.048	36.6 ± 10.2
No. of catheter-dependent HD days > 30 (%) ^a	4 (26.7)	18 (66.7)	0.023	22 (52.4)
ICU stay at the time of bacteremia	4 (26.7)	16 (59.3)	0.058	20 (47.6)

^a Variable with a p-value < 0.05 by multivariate analysis, CRB: catheter-related bacteremia.

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