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Table 3 Univariate and multivariable analyses of risk factors for death in serogroup C and A meningococcal infection in Hefei, 2000–2010

From: Emergence of serogroup C meningococcal disease associated with a high mortality rate in Hefei, China

Characteristic Mortality rate, no. of deaths/no. of patients (%) Univariate analysis Multivariable analysis
OR (95% CI) P OR (95% CI) p
Sex      
  Female 25/263(9.5) Reference    
  Female 25/263(9.5) Reference    
Age, years      
  <1 4 /23(1.7) Reference <0.001 Reference <0.001
  1-4 10/126(7.9) 0.08(0.03-0.13)   0.20 (0.11–0.38)  
  5-14 12/209(5.7) 0.06(0.02-0.1)   0.13 (0.07–0.27)  
  15-24 37 /224(16.5) 0.17(0.13-0.2)   0.97 (0.24–3.86) 15-24
  25-44 1/66(1.5) 0.02(0.01-0.09)   0.13 (0.07–0.27) 25-44
  >44 0/7(0) Undefined   Undefined >44
Syndrome a      
  Meningitis 9/200(4.5) Reference 0.003 Reference 0.002
  Meningococcemia 55/455(12.1) 2.92(1.41-6.02)   3.21 (0.89–11.56)  
Serogroup      
  A 9/171(5.3) Reference 0.021 Reference 0.053
  C 55/484(11.4) 2.31(1.12-4.78)   2.73 (0.69–10.87)  
Strain’s susceptibility to penicillin      
  Susceptible 37/288(12.8) Reference 0.388   
  Non-susceptible 9/52(17.3) 0.70(0.32-1.56)    
  1. a Two cases of arthritis with positive synovial fluid culture results were excluded.