Table 3 Univariate and multivariable analyses of risk factors for death in serogroup C and A meningococcal infection in Hefei, 2000–2010
From: Emergence of serogroup C meningococcal disease associated with a high mortality rate in Hefei, China
Characteristic | Mortality rate, no. of deaths/no. of patients (%) | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | p | ||
Sex | |||||
Female | 25/263(9.5) | Reference | |||
Female | 25/263(9.5) | Reference | |||
Age, years | |||||
<1 | 4 /23(1.7) | Reference | <0.001 | Reference | <0.001 |
1-4 | 10/126(7.9) | 0.08(0.03-0.13) | 0.20 (0.11–0.38) | ||
5-14 | 12/209(5.7) | 0.06(0.02-0.1) | 0.13 (0.07–0.27) | ||
15-24 | 37 /224(16.5) | 0.17(0.13-0.2) | 0.97 (0.24–3.86) | 15-24 | |
25-44 | 1/66(1.5) | 0.02(0.01-0.09) | 0.13 (0.07–0.27) | 25-44 | |
>44 | 0/7(0) | Undefined | Undefined | >44 | |
Syndrome a | |||||
Meningitis | 9/200(4.5) | Reference | 0.003 | Reference | 0.002 |
Meningococcemia | 55/455(12.1) | 2.92(1.41-6.02) | 3.21 (0.89–11.56) | ||
Serogroup | |||||
A | 9/171(5.3) | Reference | 0.021 | Reference | 0.053 |
C | 55/484(11.4) | 2.31(1.12-4.78) | 2.73 (0.69–10.87) | ||
Strain’s susceptibility to penicillin | |||||
Susceptible | 37/288(12.8) | Reference | 0.388 | ||
Non-susceptible | 9/52(17.3) | 0.70(0.32-1.56) | |||