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Table 3 Insulin resistance indices according to lipodystrophy defined clinically and by FMR

From: Lipodystrophy defined by Fat Mass Ratio in HIV-infected patients is associated with a high prevalence of glucose disturbances and insulin resistance

Lipodystrophy defined clinically

defined by FMR

 

Total

Without CL

With CL

P

Without L

With L

P

HOMA-IR [median (IQR)]

1.9 (2.8)

1.7 (2.4)

2.1 (3.0)

0.229

1.6 (2.6)

2.8 (2.8)

<0.001

HOMA-B [median (IQR)]

92.3 (106.4)

92.3 (91.1)

91.8 (117.5)

0.855

92.3 (96.1)

85.4 (120.8)

0.633

QUICKI [median (IQR)]

0.34 (0.06)

0.35 (0.06)

0.34 (0.06)

0.229

0.36 (0.07)

0.33 (0.05)

<0.001

MATSUDA [median (IQR)]

4.8 (5.1)

5.0 (4.2)

4.7 (5.4)

0.735

5.9 (5.3)

4.1 (4.4)

0.002

Glucose [mg/dL, median (IQR)]

93.5 (26.0)

90.0 (23.0)

97.0 (35.5)

0.046

90.0 (23.0)

97.0 (35.5)

0.002

Insulin [μU/mL, median (IQR)]

8.1 (9.6)

7.9 (8.2)

9.0 (10.2)

0.365

7.5 (8.1)

10.1 (9.9)

0.003

A1c [% median (IQR)]

5.3 (0.7)

5.2 (0.6)

5.3 (0.9)

0.091

5.2 (0.6)

5.5 (0.9)

0.002

  1. (CL- clinical lipodystrophy; L- lipodystrophy).