Table 2 Percentage (with 95% confidence intervals) of subjects reporting solicited local (injection site) symptoms within 7 days after the first and after the second dose of H1N1 vaccine in adults aged 18 to 60 years and in adults >60 years
Symptom | Intensity | Group A Vaccinated on Day 0 and Day 21 | Group B Vaccinated on Day 0 and Day 182 | ||
|---|---|---|---|---|---|
Dose 1% (95% CI) | |||||
18-60 years N = 92 | >60 years N = 90 | 18-60 years N = 70 | >60 years N = 52 | ||
Pain | Any | 94.6 | 78.9 | 95.7 | 67.3 |
(87.8-98.2) | (69.0-86.8) | (88.0-99.1) | (52.9-79.7) | ||
Grade 3* | 0.0 | 2.2 | 0.0 | 0.0 | |
(0.0-3.9) | (0.3-7.8) | (0.0-5.1) | (0.0-6.8) | ||
Redness | Any | 10.9 | 8.9 | 11.4 | 1.9 |
(5.3-19.1) | (3.9-16.8) | (5.1-21.3) | (0.0-10.3) | ||
>100 mm | 0.0 | 0.0 | 0.0 | 0.0 | |
(0.0-3.9) | (0.0-4.0) | (0.0-5.1) | (0.0-6.8) | ||
Swelling | Any | 12.0 | 6.7 | 8.6 | 1.9 |
(6.1-20.4) | (2.5-13.9) | (3.2-17.7) | (0.0-10.3) | ||
>100 mm | 0.0 | 0.0 | 0.0 | 0.0 | |
(0.0-3.9) | (0.0-4.0) | (0.0-5.1) | (0.0-6.8) | ||
Dose 2% (95% CI) | |||||
18-60 years N = 91 | >60 years N = 85 | 18-60 years N = 60 | >60 years N = 45 | ||
Pain | Any | 87.9 | 72.9 | 90.0 | 57.8 |
(79.4-93.8) | (62.2-82.0) | (79.5-96.2) | (42.2-72.3) | ||
Grade 3* | 2.2 | 0.0 | 5.0 | 0.0 | |
(0.3-7.7) | (0.0-4.2) | (1.0-13.9) | (0.0-7.9) | ||
Redness | Any | 6.6 | 12.9 | 10.0 | 6.7 |
(2.5-13.8) | (6.6-22.0) | (3.8-20.5) | (1.4-18.3) | ||
>100 mm | 0.0 | 0.0 | 3.3 | 2.2 | |
(0.0-4.0) | (0.0-4.2) | (0.4-11.5) | (0.1-11.8) | ||
Swelling | Any | 8.8 | 11.8 | 16.7 | 8.9 |
(3.9-16.6) | (5.8-20.6) | (8.3-28.5) | (2.5-21.2) | ||
>100 mm | 0.0 | 0.0 | 0.0 | 0.0 | |
(0.0-4.0) | (0.0-4.2) | (0.0-6.0) | (0.0-7.9) | ||