Residual risk of transfusion-transmitted infection with human immunodeficiency virus, hepatitis C virus, and hepatitis B virus in Korea from 2000 through 2010

Table 3 Residual risk of transmitting viral infection by transfusing seronegative units donated from 2000 to 2010

	2000-2001	2002-2003	2004-2005	2006-2007	2008-2009	p-value of Poisson regression analysis
HIV
No. of seroconvertors	-	-	17	10	16
Incidence rate per 100,000 person-yr	-	-	1.99	1.31	1.83
(95% CI)*			(0~8.30)	(0~6.51)	(0~7.81)
Residual risk (per 100,000 donations)	-	-	0.09	0.04	0.06	p = 0.745
(95% CI)			(0~1.43)	(0~0.95)	(0~1.14)
RR (1 in)	-	-	1,080,244	2,534,406	1,813,998
HCV
No. of seroconvertors	64	31	23	14	7
Incidence rate per 100,000 person-yr	6.80	3.19	2.69	1.83	0.80
(95% CI)	(0~18.34)	(0~11.00)	(0~10.02)	(0~7.97)	(0~4.76)
Residual risk (per 100,000 donations)	1.23	0.58	0.28	0.05	0.02	p = 0.001
(95% CI)	(0~6.14)	(0~3.91)	(0~2.65)	(0~1.07)	(0~0.65)
RR (1 in)	81,431	173,611	357,197	1,991,405	4,560,879
HBV
No. of seroconvertors	126	121	105	175	105
Incidence rate per 100,000 person-yr	13.48	12.49	12.30	22.87	11.96
(95% CI)	(0~29.73)	(0~27.95)	(0~27.98)	(1.16~44.58)	(0~27.25)
Residual risk (per 100,000 donations)	2.18	2.20	1.99	3.48	1.47	p = 0.885
(95% CI)	(0~8.72)	0~8.69)	(0~8.30)	(0~11.95)	(0~6.83)
RR (1 in)	45,891	49,515	50,218	28,754	67,826

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