Table 1 Patient characteristics
Characteristic | L-AmB (n = 60) | CAS (n = 60) |
|---|---|---|
No. of patients (%) | ||
Gender | ||
male | 33 (55.0) | 38 (63.3) |
female | 27 (45.0) | 22 (36.7) |
Age group | ||
< 6 yr. | 20 (33.3) | 17 (28.3) |
6 - 11 yr. | 24 (40.0) | 20 (33.3) |
12 - < 18 yr. | 16 (26.7) | 23 (38.3) |
Donor | ||
MUD | 20 (33.3) | 19 (31.7) |
MMUD | 4 (6.7) | 1 (1.7) |
MMFD | 29 (48.3) | 23 (38.3) |
MFD | 7 (11.7) | 17 (28.3) |
Primary diagnosis | ||
ALL | 18 (30.0) | 17 (28.3) |
AML | 7 (11.7) | 1 (1.7) |
JMML | 3 (5.0) | 2 (3.3) |
CML | 3 (5.0) | - |
MDS | 6 (10.0) | 5 (8.3) |
NHL | 1 (1.7) | 3 (5.0) |
Solid tumors | 9 (15.0) | 10 (16.7) |
Aplastic anemia | 1 (1.7) | 10 (16.7) |
Neurometabolic diseases | 5 (8.3) | 5 (8.3) |
Immunodeficiency | 4 (6.7) | 7 (11.7) |
Chediak-Higashi-syndrome | 2 (3.3) | - |
Morbus Kostmann | 1 (1.7) | - |
Graft-versus-Host Disease | ||
Grade I | 22 (36.7) | 24 (40.0) |
Grade II | 4 (6.7) | 5 (8.3) |
Grade III | 2 (3.3) | 2 (3.3) |
Grade IV | 2 (3.3) | 2 (3.3) |
Chronic limited | 1 (1.7) | 3 (5.3) |
Chronic extensive | 1 (1.7) | 1 (1.7) |