Figure 2From: Caspofungin as antifungal prophylaxis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis Hepatotoxicity. Values are shown at baseline before conditioning (baseline), day 0, maximum during therapy (maximum), and end of intravenous antimycotic monoprophylaxis (end) with L-AmB (open bars) and CAS (shaded bars). A: Mean and standard deviation (SD) of plasma alanine aminotransferase (ALT) (normal value ≤ 39 U/L), B: Plasma aspartate aminotransferase (AST) (normal value ≤ 39 U/L), C: Total plasma bilirubin (normal value ≤ 1.1 mg/dl), D: Direct plasma bilirubin (normal value ≤ 0.3 mg/dl), and E: Plasma alkaline phosphatase (AP) (normal value ≤ 320 U/L). The horizontal line shows the normal value. Differences were tested for significance by the Wilcoxon Matched-Pairs Signed Rank Test (Table 2).Back to article page