Table 1 Demographics and clinical characteristics of patients infected or colonized by extended-spectrum β-lactamase producing Escherichia coli
Total episodes (n = 202) | Hospital-onset (n = 95) | Community-onset | |||
|---|---|---|---|---|---|
Total (n = 107) | Healthcare-associated (n = 62) | Community-associated (n = 45) | |||
Age, year, mean (range) | 60 (0–97) | 68.3 (5–97) | 52.7 (0–85) | 64.3 (0–85) | 36.7 (0–85) |
Gender, M: F | 79:123 | 50:45 | 29:78 | 19:43 | 10:35 |
Healthcare-associated risk factors | |||||
Previous Admission | 89 (44.1) | 41 (43.2) | 48 (44.9) | 48 (77.4) | NAa |
History of long term care facility stay | 34 (16.8) | 20 (21.1) | 14 (13.1) | 14 (22.6) | NAa |
Hemodialysis | 16 (7.9) | 9 (9.5) | 7 (6.5) | 7 (11.3) | NAa |
Surgery/invasive procedures | 56 (27.7) | 46 (48.4) | 10 (9.3) | 10 (16.1) | NAa |
Co-morbidity | |||||
Cerebrovascular disease | 85 (42.1) | 63 (66.3) | 22 (20.6) | 18 (29.0) | 4 (8.9) |
Diabetes | 68 (33.7) | 40 (42.1) | 28 (26.2) | 22 (35.5) | 6 (13.3) |
Chronic kidney disease | 48 (23.8) | 17 (17.9) | 31 (29.0) | 25 (40.3) | 6 (13.3) |
Malignancy | 40 (19.8) | 22 (23.3) | 18 (16.8) | 16 (25.8) | 2 (4.4) |
Heart failure | 27 (13.4) | 20 (21.1) | 7 (6.5) | 5 (8.1) | 2 (4.4) |
Chronic lung disease | 18 (8.9) | 15 (15.8) | 3 (2.8) | 2 (3.2) | 1 (2.2) |
Liver cirrhosis | 14 (6.98) | 7 (7.4) | 7 (6.5) | 7 (11.3) | 0 (0) |
Transplant | 6 (3.0) | 3 (3.2) | 3 (2.8) | 1 (1.6) | 2 (4.4) |
Obstructive uropathy | 18 (8.9) | 1 (1.1) | 17 (15.9) | 12 (19.4) | 5 (11.1) |
Vascular catheter | 58 (28.7) | 55 (57.9) | 3 (2.8) | 3 (4.8) | 0 (0) |
Urinary catheter | 94 (46.5) | 76 (80) | 18 (16.8) | 18 (29) | 0 (0) |
Recent use of antibiotics | 141 (69.8) | 88 (92.6) | 53 (49.5) | 34 (54.8) | 19 (69.8) |
Infection: colonization | 105:97 | 34:61 | 71:36 | 41:21 | 30:15 |
Type of infection | |||||
Bloodstream infection | 23 (11.4) | 4 (11.8) | 19 (26.8) | 12 (29.3) | 7 (23.3) |
Urinary tract infection | 49 (24.3) | 5 (14.7) | 44 (44) | 23 (56.1) | 21 (70) |
Lung infection | 20 (9.9) | 17 (50) | 3 (4.2) | 3 (7.3) | 0 (0) |
Intra-abdominal infection | 5 (4.8) | 5 (14.7) | 1 (1.4) | 1 (2.4) | 0 (0) |
SSTb/bone infection | 5 (6.7) | 3 (8.8) | 4 (5.6) | 2 (4.9) | 2 (6.7) |
Colonization site | |||||
Urine | 56 (54.6) | 28 (45.9) | 25 (69.4) | 13 (61.9) | 12 (80) |
Respiratory tract | 23 (23.7) | 20 (32.8) | 3 (8.3) | 3 (14.3) | 0 (0) |
Wound | 8 (8.2) | 8 (13.1) | 0 (0) | 0 (0) | 0 (0) |
Bile | 4 (4.1) | 1 (1.6) | 3 (8.3) | 3 (14.3) | 0 (0) |
Others | 9 (9.3) | 4 (6.6) | 5 (13.9) | 2 (9.5) | 3 (20) |
No. of isolates collected | 142 (70.3) | 61 (64.2) | 81 (75.7) | 46 (74.2) | 35 (77.8) |