Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya

Table 5 Environmental factors associated with adherence to ACT in Southeast Alego location

Independent variables	Adhered	Did not adhere	P-value^a	OR	95 % CI	P-value^b
Environmental factors
Source of ACT
Health facility	132 (95.7 %)	144 (91.7 %)	0.162	1.00 (reference category)
Bought drugs from Chemist	2 (1.4 %)	1 (0.6 %)		0.458	0.041-5.114	0.526
Left-over, given by neighbour /friend /relative	4 (2.9 %)	12 (7.6 %)		2.750	0.866-8.737	0.086
Availability at source
No	60 (42.9 %)	97 (61.8 %)	0.001	1.00 (reference category)
Yes	80 (57.1 %)	60 (38.2 %)		0.464	0.292-0.738	0.001
Distance to source
≤ 30 minutes	67 (47.9 %)	66 (42.0 %)	0.350	1.00 (reference category)
> 30 minutes	73 (52.1 %)	91 (58.0 %)		1.265	0.800-2.002	0.314

Legend: HH- Household; ACT- Artemisinin-based Combination Therapy. The results above show that availability of ACT at the source was significantly associated with adherence to the drug and it was not associated to the source and distance to source of ACT. P-value in bold is statistically significant at P ≤ 0.050. ^aStatistical significance determined by Chi-square tests. ^bStatistical significance determined by logistic regression tests.

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