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Table 5 Diagnostic accuracy in all sputum smear-negative TB suspects

From: Fiberoptic bronchoscopy for the rapid diagnosis of smear-negative pulmonary tuberculosis

 

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

+LR (95% CI)

−LR (95% CI)

FOB

0.759 (0.690–0.786)

0.972 (0.920–0.992)

0.953 (0.867–0.987)

0.843 (0.798–0.861)

27.333 (8.674–99.257)

0.248 (0.216–0.337)

CT

0.852 (0.752–0.923)

0.722 (0.647–0.776)

0.697 (0.615–0.755)

0.867 (0.777–0.931)

3.067 (2.131–4.117)

0.205 (0.099–0.383)

FOB + CT

0.963 (0.879–0.993)

0.708 (0.645–0.731)

0.712 (0.650–0.735)

0.962 (0.876–0.993)

3.302 (2.477–3.696)

0.052 (0.009–0.188)

  1. Definition of abbreviations: TB = tuberculosis, PPV = positive predictive value, NPV = negative predictive value, +LR = positive likelihood ratio, -LR = negative likelihood ratio, 95% CI = 95% confidence interval, FOB = fiberoptic bronchoscopy, CT = computed tomography.