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Table 5 Diagnostic accuracy in all sputum smear-negative TB suspects

From: Fiberoptic bronchoscopy for the rapid diagnosis of smear-negative pulmonary tuberculosis

  Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) +LR (95% CI) −LR (95% CI)
FOB 0.759 (0.690–0.786) 0.972 (0.920–0.992) 0.953 (0.867–0.987) 0.843 (0.798–0.861) 27.333 (8.674–99.257) 0.248 (0.216–0.337)
CT 0.852 (0.752–0.923) 0.722 (0.647–0.776) 0.697 (0.615–0.755) 0.867 (0.777–0.931) 3.067 (2.131–4.117) 0.205 (0.099–0.383)
FOB + CT 0.963 (0.879–0.993) 0.708 (0.645–0.731) 0.712 (0.650–0.735) 0.962 (0.876–0.993) 3.302 (2.477–3.696) 0.052 (0.009–0.188)
  1. Definition of abbreviations: TB = tuberculosis, PPV = positive predictive value, NPV = negative predictive value, +LR = positive likelihood ratio, -LR = negative likelihood ratio, 95% CI = 95% confidence interval, FOB = fiberoptic bronchoscopy, CT = computed tomography.