Table 1 Patient Demographics in Evaluable Population
From: Daptomycin Therapy for Osteomyelitis: A Retrospective Study
Characteristics | Total (n = 71) |
|---|---|
Gender | |
Female | 36 (51) |
Male | 35 (49) |
Age group (years) | |
≤ 50 | 20 (28) |
51-65 | 24 (33) |
≥ 66 | 27 (38) |
Weight, kg (median [min, max]) | 82 [37, 136] |
Type of osteomyelitis | |
Contiguous | 45 (63) |
Hematogenous | 12 (17) |
Unknown | 14 (20) |
Chronic presentation | 29 (41) |
Anatomic site | |
Foot/Toe | 38 (54) |
Vertebrae | 13 (18) |
Sacrum | 5 (7) |
Sternum | 4 (6) |
Tibia/Fibula | 3 (4) |
Knee | 2 (3) |
Skull | 2 (3) |
Femur | 1 (1) |
Finger | 1 (1) |
Rib | 1 (1) |
Other | 1 (1) |
Multiple osteomyelitis sites | 6 (8) |
Concomitant infections | |
Skin and skin structure infection† | 9 (13) |
Bacteremia | 5 (7) |
Deep surgical site infection | 5 (7) |
Urinary tract infection/pyelonephritis | 3 (4) |
Septic arthritis | 1 (1) |
Underlying diseases* | |
Hypertension | 34 (48) |
Diabetes mellitus | 31 (44) |
Other cardiovascular disease | 10 (14) |
Peripheral vascular disease | 13 (18) |
Anemia/All hematologic diseases | 10 (14) |
Cardiac Arrhythmias | 10 (14) |
ICU stay during daptomycin | 6 (9) |
Initial CrCl < 30 ml/min | 3 (4) |
On dialysis | 0 (0) |