|
Patient groups
|
Day
|
Renal biomarkers
|
Hepatic Biomarkers
|
|---|
|
Creatinine (mg/dL)b
|
Urea (mg/dL)b
|
ALT (U/L)b
|
γ-GT (U/L)b
|
|---|
|
Intervention
|
1
|
0.51 ± 0.04
|
21.3 ± 3
|
15.5 ± 1.6
|
11.4 ± 0.8
|
|
4
|
0.43 ± 0.02
|
18 ± 1.1
|
21.9 ± 2.3
|
11 ± 0.6
|
|
Placebo
|
1
|
0.49 ± 0.03
|
18.7 ± 2.6
|
18.6 ± 2.2
|
13.4 ± 2.7
|
| |
4
|
0.40 ± 0.02
|
17.3 ± 1.5
|
21.1 ± 2.4
|
18.9 ± 4
|
-
Abbreviation:
ALT Alanine transaminase, γ−GT Gamma glutamyl transferase.
-
aData are given as mean ± standard error of mean.
-
bNormal reference values of creatinine: 0.6-1.2 mg/dL (men) and 0.5-1.1 mg/dL (women); urea: 6-24 mg/dL; ALT: 0.01-41U/L (men) and 0.01-31.0U/L (women) and γ−GT 9-40U/L (men) and 0-35U/L (women).
