Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial

Table 4 Levels of hepatic and renal biomarkers in serum of Shigella -infected patients at different time ^a

Patient groups	Day	Renal biomarkers		Hepatic Biomarkers
Patient groups	Day	Creatinine (mg/dL)^b	Urea (mg/dL)^b	ALT (U/L)^b	γ-GT (U/L)^b
Intervention	1	0.51 ± 0.04	21.3 ± 3	15.5 ± 1.6	11.4 ± 0.8
Intervention	4	0.43 ± 0.02	18 ± 1.1	21.9 ± 2.3	11 ± 0.6
Placebo	1	0.49 ± 0.03	18.7 ± 2.6	18.6 ± 2.2	13.4 ± 2.7
	4	0.40 ± 0.02	17.3 ± 1.5	21.1 ± 2.4	18.9 ± 4

Abbreviation: ALT Alanine transaminase, γ−GT Gamma glutamyl transferase.
^aData are given as mean ± standard error of mean.
^bNormal reference values of creatinine: 0.6-1.2 mg/dL (men) and 0.5-1.1 mg/dL (women); urea: 6-24 mg/dL; ALT: 0.01-41U/L (men) and 0.01-31.0U/L (women) and γ−GT 9-40U/L (men) and 0-35U/L (women).

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