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Table 2 Baseline demographic and clinic data and risk factors for AAD

From: A multicentre randomised controlled trial evaluating lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea in older people admitted to hospital: the PLACIDE study protocol

Variable Units or Categories where appropriate
· Age years
· Sex male; female
· Race white; black; Asian; Chinese; other
· Period of recruitment summer (May – Sept); winter (Oct-March)
· Smoking usual number of cigarettes/day
· Alcohol usual number of units/week
· Where admitted from home; residential care; other hospital; other
· Admission type emergency/unplanned; elective/ planned for procedure or investigation
· Admission diagnosis or main cause of admission  
· Co-morbidity hypertension; asthma; diabetes; chronic obstructive airways disease; renal disease; irritable bowel syndrome; dementia; Alzheimer’s disease; other
· Previous GI surgery  
· Number of hospital admissions in last eight weeks  
· Antacid treatment antacid; H2-receptor antagonist; proton pump inhibitor
· Naso-gastric tube in-situ  
· Duration of hospital stay prior to recruitment days
· Indication for antibiotic treatment  
· Antibiotic treatment: antibiotic used1 single class; 2 classes; 3 or more classes
· Antibiotic treatment: total duration single dose; 1–6 days; 7–13  days; ≥14 days
  1. 1Antibiotics will be classified according to British National Formulary categories (http://www.bnf.org): Penicillins (sub-classified as benzylpenicillin, penicillinase resistant penicillin, broad-spectrum penicillins, anti-pseudomonas penicillins); Cephalosporins (sub-classified as 1st, 2nd and 3rd generation); Carbapenems and other beta-lactams; Tetracyclines; Aminoglycosides; Macrolides; Clindamycin; Sulphonamides and trimethoprim; Metronidazole; Quinolones; Glycopeptides; TB drugs; other.