Dynamic analysis of Th1/Th2 cytokine concentration during antiretroviral therapy of HIV-1/HCV co-infected Patients

Table 2 Correlation between the concentration of Th1/Th2 cytokines, CD4⁺ T lymphocyte count, virus load and Th1/Th2 cytokine ratio

Correlation Coefficient	CD4	VL	IFN-γ	TNF-α	IL-2	Th1 cytokines	IL-10	IL-5	IL-4	Th2 cytokines	Th1/Th2 ratio
CD4	1.000	-0.519^a	-0.192	0.262	-0.335^a	-0.112	-0.019	-0.317^a	0.108	0.121	-0.236^b
VL	-0.519^a	1.000	0.537^a	-0.405^b	0.592^a	0.534^a	0.381^a	0.360^a	0.112	0.295^b	0.383^a
IFN-γ	-0.192	0.537^a	1.000	-0.229	0.443^a	0.969^a	0.286^b	0.315^a	0.383^a	0.498^a	0.701^a
TNF-α	0.262	-0.405^b	-0.229	1.000	-0.257	-0.092	0.043	-0.115	0.157	0.117	-0.214
IL-2	-0.335^a	0.592^a	0.443^a	-0.257	1.000	0.407^a	0.510^a	0.430^a	0.298^b	0.334^a	0.287^b
Th1 cytokines	-0.112	0.534^a	0.969^a	-0.092	0.407^a	1.000	0.270^b	0.278^b	0.329^b	0.486^a	0.775^a
IL-10	-0.019	0.381^a	0.286^b	0.043	0.510^a	0.270^b	1.000	0.362^a	0.290^b	0.690^a	-0.155
IL-5	-0.317^a	0.360^a	0.315^a	-0.115	0.430^a	0.278^b	0.362^a	1.000	0.233	0.433^a	0.139
IL-4	0.108	0.112	0.383^a	0.157	0.298^b	0.329^b	0.290^b	0.233	1.000	0.668^a	-0.009
Th2 cytokines	0.121	0.295^b	0.498^a	0.117	0.334^a	0.486^a	0.690^a	0.433^a	0.668^a	1.000	-0.104

Each data represents the correlation coefficient betwwen horizontal and vertical effectors which are overlapped.
a. Correlation is significant at the 0.01 level (2-tailed)
b. Correlation is significant at the 0.05 level (2-tailed)

ISSN: 1471-2334