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Table 2 Abilities of resuscitation promoting factors (rpfs) to discriminate between TB disease and no TB.

From: Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting

Antigen TB cases HHCs P-value AUC Cut-off Sensitivity
(%)
Specificity
(%)
Rv0867c 0.0
(0.0-274.6)
52.2 (0.0-2173.3) < 0.001 0.80 < 1.3 78 (18/23) 85 (17/20)
Rv2389c 0.0
(0.0-209.2)
25.8 (0.0-1056.0) 0.002 0.78 < 0.9 78 (18/23) 80 (16/20)
Rv2450c 0.0
(0.0-209.8)
29.2 (0.0-1123.5) 0.003 0.76 < 10.3 74 (17/23) 80 (16/20)
Rv1009 0.0
(0.0-184.2)
27.2 (0.0-1875.0) 0.001 0.79 < 0.3 78 (13/23) 80 (16/20)
Rv1884c 0.0
(0.0-158.3)
4.0 (0.0-481.1) 0.012 0.72 < 1.3 87 (20/23) 60 (12/20)
  1. Median levels of IFN-γ (pg/ml) and ranges (in parenthesis) elicited upon stimulation of whole blood with rpfs and ability to discriminate between pulmonary TB (in 23 cases) and no TB disease (in 20 HHCs). AUC = Area under the ROC curve