Economic burden of vulvar and vaginal intraepithelial neoplasia: retrospective cost study at a German dysplasia centre

Table 1 Age, surgical interventions and visits to gynaecologists for diagnostic purposes

	Subgroup I			Subgroup II
	Total analysis period	Main analysis period		Total analysis period	Main analysis period
N	52	52	n	42	42
Age at first SI (years) mean ± SD [range]	49.2 ± 13.8 [22-81]		Age at first SI (years) mean ± SD [range]	43.6 ± 10.3 [21-71]	46.8 ± 10.4 [21-77]
Number of SI/pat.	1		Number of SI/pat.	2 - 5	1 - 5
Mean SI/pat. ± SD	1		Mean SI/pat. ± SD	3.0 ± 1.19	1.74 ± 0.91
Setting of SI			Setting of SI
Inpatient	30		inpatient	64	32
Outpatient	21		outpatient	42	31
n/a	1		n/a	20	10
Total	52		Total	126	73
Number of VDP mean ± SD [range]	2.33 ± 1.64 [1–7]	1.54 ± 0.54 [1–3]	Number of VDP mean ± SD [range]	6.26 ± 7.41 [1-41]	2.07 ± 1.24 [0-5]
Diagnoses			Diagnoses in SI history
VIN2	7		VIN2	1	5
VIN3	40		VIN3	26	30
VIN2&VIN3	1		VIN2 - VIN3	11	3
VaIN2	2		VIN3 - VIN3&VaIN2	1	1
VIN3&VaIN3	2		VIN3 - VIN3&VaIN3	2	2
			VIN3&VaIN2	1	1
Total	52		Total	42	42

Subgroup I: women who underwent one VIN 2/3 and/or VaIN 2/3 related surgery.
Subgroup II: women subjected to two or more VIN 2/3 and/or VaIN 2/3 related surgeries.
Total analysis period: period from first VIN 2/3 or VaIN 2/3 related to the last reported contact.
Main analysis period: period of one year before the reference intervention.
SI: surgical intervention(s).
VDP: visit(s) at dysplasia outpatient department or office based specialist for diagnostic purposes.

ISSN: 1471-2334