Timely HAART initiation may pave the way for a better viral control

BMC Infectious Diseases

Table 3 Late subjects with deferred treatment of acute HIV-1 infection.

ID	Therapy^†	Elapsed days ^‡	Days on therapy	Days out therapy	At diagnosis*			At first interruption
					CD4	CD8	vRNA	CD4	CD8	vRNA
Pt 07	AZT, 3TC	300	1303	606	463	2498	34000	614	3101	9154
Pt 12	D4T, 3TC, SQV	26	1117	89	422	754	62000	601	948	< 50
Pt 16	AZT, ddC, Rit	9	1803	66	116	1170	990000	483	1165	< 50
Pt 17	AZT, 3TC	49	1872	412	51	1155	110000	693	1359	150
Pt 18	AZT, ddl	268	1615	558	340	994	35000	989	1172	< 50
Pt 19	AZT, 3TC	393	819	206	559	1230	70319	616	825	< 50
Pt 20	AZT, 3TC	15	2503	21	235	877	230000	566	1246	< 50
Pt 22	D4T, 3TC	0	1807	64	290		140000	1334		< 50
Pt 23	AZT, 3TC	483	2109	248	409	734	47000	686	572	< 50
Pt 25	D4T,3TC, IDV	22	1661	625	383	809	37000	896	1208	< 50
Pt 26	AZT, 3TC	38	841	1150	540	1256	16000	719	640	< 50
Pt 27	AZT,3TC	10	1885	50	332		2800	636		< 50
Pt 28	AZT,3TC,EFV	0	3131	373	556		1900	752		< 50
Pt 29	AZT,3TC,Lop/rit	21	1950	69	483		150000	1233		100
Pt 31	AZT,3TC,IDV	0	1255	109	574	1625	7900	813	640	< 50
Pt 32	AZT,3TC,IDV	0	1472	160	393		1335	1235		< 50
Pt 33	D4T, 3TC	407	523	66	479	494	473	705	450	< 50
Pt 34	ddl, D4T, NVP	13	2207	54	493	1628	230000	907	943	< 50
Pt 38	AZT,3TC,LPV	0	1460	270	481	1156	20000	534	964	< 50
Pt 39	AZT,3TC,NVP	64	2734	767	539		41000	859		< 50
Pt 41	AZT,3TC,Lop/rit	62	428	89	200		135000	848		< 50

Clinical information about the twenty-one patients selected at the Clinical Department of the National Institute for Infectious Disease "L. Spallanzani" in Rome. All subjects received HAART during chronic phase of infection.
^†AZT, Retrovir (Zidovudine); 3TC, Epivir (Lamivudine); D4T, Zerit (Staduvine); SQV, Saquinvir (Invirase); Zalcitabina (ddC, Hivid); Rit, Ritonavir (Norvir); ddl, Didanosine (Videx); IDV, Indinavir (Crix-ivan); EFV, Efavirenz; NVP, Nevirapine (Viramune); LPV (Lop), Lopinavir; ^‡ Days elapsed from diagnosis (enrollment) to initiation of HAART. *CD4 and CD8 are per microlitre of plasma, viremia is per millilitre of plasma.

ISSN: 1471-2334