Skip to main content

Advertisement

Table 2 Early subjects with an immediate treatment of acute HIV-1 infection.

From: Timely HAART initiation may pave the way for a better viral control

ID Therapy Elapsed days Days on therapy Days out therapy At diagnosis* At first interruption
      CD4 CD8 vRNA CD4 CD8 vRNA
Pt 03 D4T,3TC,IDV 14 1775 27 653 1659 75 809 459 5794
Pt 05 AZT,3TC,IDV 61 1657 27 444 633 100 867 476 < 50
Pt 29 AZT,3TC,NFV 14 1069 28 1103 1964 31 741 844 < 50
Pt 33 AZT,3TC,IDV 66 925 28 424 991 0.13 458 474 147
Pt 35 AZT,3TC,EFV 1 1041 30 522 1205 78 919 607 496
Pt 37 AZT,3TC,EFV 0 1371 790 545 1233 3.9 901 384 < 50
Pt 58 AZT,3TC,EFV 3 442 27 768 1632 50 1451 1580 < 50
Pt 06 AZT,3TC,IDV 32 1620 1908 882 4146 4.1 754 726 < 50
Pt 18 AZT,3TC,IDV 26 635 213 1319 1810 15 1718 825 < 80
Pt 24 AZT,3TC,IDV 3 1231 542 507 3162 78 513 1067 < 50
Pt 31 AZT,3TC,EFV 19 1102 1654 322 243 490 1154 1165 < 50
Pt 41 AZT,3TC,EFV 12 705 1837 568 278 130 1326 940 < 50
Pt 45 AZT,3TC,EFV 5 488 55 307 1032 130 872 506 < 50
Pt 53 AZT,3TC,Lop/rit 16 503 179 341 779 18.9 545 529 150
Pt 04 AZT,3TC,IDV 6 1561 2155 603 1288 1.6 1047 1015 88
Pt 19 AZT,3TC,IDV 13 1480 1640 1338 716 10 1113 447 < 50
Pt 28 AZT,3TC,NFV 7 325 70 281 860 190 863 485 < 80
Pt 32 AZT,3TC,EFV 15 1384 669 409 1448 4.3 960 331 < 50
Pt 72 AZT,3TC,LPV 7 318 343 827 386 19 1005 751 < 50
Pt 81 AZT,3TC,NVP 33 745 317 412 264 32.5 522 461 68
Pt 85 AZT,3TC,Lop/rit 46 717 717 326 669 50 855 1436 < 50
Pt 92 3TC,Lop/rit,TNF 0 455 331 616 3774 46.3 1027 913 < 50
  1. Clinical information about the twenty-two patients selected at the Clinical Department of the National Institute for Infectious Disease "L. Spallanzani" in Rome. All subjects received HAART within six months from primary infection.
  2. D4T, staduvine; 3TC, lamivudine; IDV, Indinavir; AZT, Zidovudine; NFV, nelflnavir; EFV, Efavirenz; NVP, nevirapine; TNF, Tenofovir; Lop, lopinavir; Rit, Ritonavir; LPV (KAL), Kaletra (lopinavir/ritonavir). Days elapsed from diagnosis (enrollment) to initiation of HAART. *CD4 and CD8 are per microlitre of plasma, viremia is per millilitre of plasma.