Figure 4

Inflammatory response. Cell counts of active macrophages (a) and dendritic cells presenting viral proteins on class II MHC molecules (b) show that, in the simulation, the late-treated case is comparable to the control case (untreated) whereas the very early case stands on its own. This suggests that the set up of an infiammatory state affects the viral rebound at therapy discontinuation. Counts are taken at week 8 for all groups. Therapy for very early started within the first week and for the late started at about week 6.