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Table 1 Group comparison of characteristics (Table 1)

From: Prognostic factors and monomicrobial necrotizing fasciitis: gram-positive versus gram-negative pathogens

  Gram positive pathogen (n = 11) Gram Negative pathogen (n = 35) p value
Age 59 (34, 72) 64(22, 85) 0.138
Gender(Male/Female) 9/2 26/9 1.000
Involved region    
   Upper extremity 5 (45.5) 10 (28.6) 0.462
   Lower extremity 6 (54.5) 25 (71.4)  
TiOA(day) 7.18 (2, 14) 2.43 (0.5, 14)* < 0.001
TiOS(hour) 25.64 (2, 72) 11.74 (1, 72)* 0.046
Immunocompromised(DM, liver dysfunction, Chronic renal failure, Malignancy) 5 (45.5) 29 (82.8)* 0.022
Comorbidity    
   DM 5 (45.5) 13 (37.1) 0.728
   Gout 5 (45.5) 2 (5.7)* 0.005
   Chronic renal failure (> 1.6 mg/dL) 2 (18.2) 7 (20) 1.000
Chronic Liver dysfunction 1 (9.1) 18 (51.4)* 0.016
   HBV 0 (0) 11 (31.4)* 0.044
   HCV 1 (9.1) 11 (31.4) 0.241
   HBV or HCV 1 (9.1) 17 (48.6)* 0.032
   Liver cirrhosis 0 8 (22.9) 0.619
ICU stay(patient number) 4 (36.4) 26 (74.3)* 0.032
Post-operative mechanical ventilation (patient number) 4 (36.4) 24 (68.6) 0.080
APACHE II score 12.9 (3, 21) 18.9 (2, 34)* 0.015
ICU stay (day) 2 (0, 7) 4.3 (0, 16) 0.077
Hospital stay (day) 35.7 (15, 70) 35.8 (13, 87) 0.800
Amputation 0 5 (10.9) 0.317
STSG 5 (45.5) 21 (60) 0.494
Free flap transfer 1 (9.1) 7 (20) 0.658
Mortality 1(9.1) 6(17.1) 1.000
  1. Data are presented as median (min, max) or frequency (%)
  2. TiOA: duration of symptoms prior to arrival in the ER
  3. TiOS: time of the first surgical intervention from arrival in the ER
  4. APACHE: Acute Physiological, Age, and Chronic Health Evaluation
  5. Chronic liver dysfunction: liver cirrhosis, viral hepatitis(HBV, or HCV)
  6. STSG: split thickness skin graft
  7. *: The difference is significant (p < 0.05)