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Table 1 Group comparison of characteristics (Table 1)

From: Prognostic factors and monomicrobial necrotizing fasciitis: gram-positive versus gram-negative pathogens

 

Gram positive pathogen (n = 11)

Gram Negative pathogen (n = 35)

p value

Age

59 (34, 72)

64(22, 85)

0.138

Gender(Male/Female)

9/2

26/9

1.000

Involved region

   

   Upper extremity

5 (45.5)

10 (28.6)

0.462

   Lower extremity

6 (54.5)

25 (71.4)

 

TiOA(day)

7.18 (2, 14)

2.43 (0.5, 14)*

< 0.001

TiOS(hour)

25.64 (2, 72)

11.74 (1, 72)*

0.046

Immunocompromised(DM, liver dysfunction, Chronic renal failure, Malignancy)

5 (45.5)

29 (82.8)*

0.022

Comorbidity

   

   DM

5 (45.5)

13 (37.1)

0.728

   Gout

5 (45.5)

2 (5.7)*

0.005

   Chronic renal failure (> 1.6 mg/dL)

2 (18.2)

7 (20)

1.000

Chronic Liver dysfunction

1 (9.1)

18 (51.4)*

0.016

   HBV

0 (0)

11 (31.4)*

0.044

   HCV

1 (9.1)

11 (31.4)

0.241

   HBV or HCV

1 (9.1)

17 (48.6)*

0.032

   Liver cirrhosis

0

8 (22.9)

0.619

ICU stay(patient number)

4 (36.4)

26 (74.3)*

0.032

Post-operative mechanical ventilation (patient number)

4 (36.4)

24 (68.6)

0.080

APACHE II score

12.9 (3, 21)

18.9 (2, 34)*

0.015

ICU stay (day)

2 (0, 7)

4.3 (0, 16)

0.077

Hospital stay (day)

35.7 (15, 70)

35.8 (13, 87)

0.800

Amputation

0

5 (10.9)

0.317

STSG

5 (45.5)

21 (60)

0.494

Free flap transfer

1 (9.1)

7 (20)

0.658

Mortality

1(9.1)

6(17.1)

1.000

  1. Data are presented as median (min, max) or frequency (%)
  2. TiOA: duration of symptoms prior to arrival in the ER
  3. TiOS: time of the first surgical intervention from arrival in the ER
  4. APACHE: Acute Physiological, Age, and Chronic Health Evaluation
  5. Chronic liver dysfunction: liver cirrhosis, viral hepatitis(HBV, or HCV)
  6. STSG: split thickness skin graft
  7. *: The difference is significant (p < 0.05)