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Table 4 Multivariate analysis of seropositivity to Coxiella burnetii in relation to different adverse pregnancy outcomes

From: Antibodies against Coxiella burnetii and pregnancy outcome during the 2007-2008 Q fever outbreaks in the Netherlands

Outcome

IgM II and IgG II ≥1:64

or IgM II ≥1:641

IgM II and IgG II ≥1:64

or IgM II ≥1:64

or IgG I and IgG II ≥1:642

 

Adjusted OR3

(95% CI)

Adjusted OR3

(95% CI)

Gestational age <37 weeks

0.7

(0.2-2.2)

0.9

(0.3-2.3)

Birth weight <2500 g

1.2

(0.4-3.4)

1.6

(0.6-3.9)

Birth weight by gestational age (<p10)

0.4

(0.1-1.8)

0.9

(0.3-2.3)

Apgar score <7

1.7

(0.4-8.2)

1.3

(0.3-5.6)

Any adverse outcome4

0.4

(0.2-1.2)

0.7

(0.3-1.5)

  1. 1 Reference category: no antibodies present, and IgG I and IgG II ≥1:64 combined
  2. 2Reference category: no antibodies present
  3. 3OR was adjusted for maternal age, parity, plurality, ethnic background, socio-economic status, urbanization, and foetal position.
  4. 4Any adverse outcome: perinatal death, birth weight <2500 g, birth weight by gestational age <p10, Apgar score <7, or gestational age <37 weeks.