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Table 4 Multivariate analysis of seropositivity to Coxiella burnetii in relation to different adverse pregnancy outcomes

From: Antibodies against Coxiella burnetii and pregnancy outcome during the 2007-2008 Q fever outbreaks in the Netherlands

Outcome IgM II and IgG II ≥1:64
or IgM II ≥1:641
IgM II and IgG II ≥1:64
or IgM II ≥1:64
or IgG I and IgG II ≥1:642
  Adjusted OR3 (95% CI) Adjusted OR3 (95% CI)
Gestational age <37 weeks 0.7 (0.2-2.2) 0.9 (0.3-2.3)
Birth weight <2500 g 1.2 (0.4-3.4) 1.6 (0.6-3.9)
Birth weight by gestational age (<p10) 0.4 (0.1-1.8) 0.9 (0.3-2.3)
Apgar score <7 1.7 (0.4-8.2) 1.3 (0.3-5.6)
Any adverse outcome4 0.4 (0.2-1.2) 0.7 (0.3-1.5)
  1. 1 Reference category: no antibodies present, and IgG I and IgG II ≥1:64 combined
  2. 2Reference category: no antibodies present
  3. 3OR was adjusted for maternal age, parity, plurality, ethnic background, socio-economic status, urbanization, and foetal position.
  4. 4Any adverse outcome: perinatal death, birth weight <2500 g, birth weight by gestational age <p10, Apgar score <7, or gestational age <37 weeks.