May 2005
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fever, cough, dyspnea
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lung (culture of sputum, chest X-ray, chest high resolution CT scan)
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133 cells/μl, VL: 40,700 copies/ml
|
lamivudine, tenofovir, efavirenz
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induction (i.v.): rifampicin 600 mg qd, levofloxacin 500 mg qd, azythromicin 500 mg qd maintenance (p.o.): levofloxacin 500 mg qd azytromicin 500 mg qd
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induction: 2 weeks maintenance: 8 weeks
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September 2009
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weight loss, fever, subcutaneous nodule in the right thigh
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subcutaneous thigh tissue (culture of granuloma, MRI, needle aspirate); colon (colonoscopy with biopsy)
|
90 cells/μl VL: 78,650 copies/ml
|
emtricitabine, tenofovir, atazanavir
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azythromicin i.v. 500 mg qd, levofloxacin i.v. 750 mg qd, ryfampicin i.v. 600 mg qd, switched to rifabutin p.o. 150 mg q48h at beginning of HAART
|
8 weeks
|
November 2009
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fever, ascites, diarrhoea
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colon, peritoneum, abdominal lymph nodes, lung (total body CT and PET scan)
|
59 cells/μl, VL: 778 copies/ml
|
emtricitabine, tenofovir, darunavir/r
|
induction (i.v.): imipenem 1 g q6h amikacin 1 g qd maintenance (p.o.): azythromicin 500 mg qd, levofloxacin 750 mg qd
|
induction: 3 weeks maintenance: 10 weeks
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March 2010
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fever, abdominal pain and intestinal bleeding
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disseminated infection (blood culture); colon (CT scan and histological examination of surgically removed colonic tissue); lung (biopsy); subcutaneous thigh tissue (culture of needle aspirate, MRI); skin.
|
62 cells/μl VL < 50 copies/ml
|
emtricitabine, tenofovir, darunavir/r
|
surgery induction (i.v.): imipenem 500 mg q6h, switched to ertapenem 1 g qd after 7 weeks, levofloxacin 750 mg qd, vancomicin 500 mg bid, azythromicin 500 mg qd maintenance (p.o.): azythromicin 500 mg qd, rifabutin 150 mg q48h
|
induction: 14 weeks maintenance: 8 weeks
|
August 2010
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headache
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CNS (brain CT scan and MRI)
|
74 cells/μl VL < 50 copies/ml
|
emtricitabine, tenofovir, darunavir/r
|
induction (i.v.): imipenem 500 mg q6h, amikacin 1 g qd maintenance (i.v.): meropenem 1 g q8h, azythromicin 500 mg qd, switched to ertapenem 1 g qd after 10 weeks
|
induction: 3 weeks maintenance: 10 weeks
|