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Table 2 Main characteristics of patients by treatment group (efavirenz vs. protease inhibitors)

From: Rate and determinants of treatment response to different antiretroviral combination strategies in subjects presenting at HIV-1 diagnosis with advanced disease

 

On efavirenz (n: 24)

On protease inhibitors (n: 78)

p value

Gender

   

   male (n: 64, 63%)

14/24, 58%

50/78, 64%

0.609

   female (n: 38, 37%)

10/24, 42%

28/78, 36%

 

Age (years)

   

   ≥ 50 (n: 27, 26%)

9/24, 37%

18/78, 23%

0.161

   < 50 (n: 75, 74%)

15/24, 62%

60/78, 77%

 

Nationality

   

   Italy (n: 83, 81%)

19/24, 79%

64/78, 82%

0.751

   Other countries (n: 19, 19%)

5/24, 21%

14/78, 18%

 

Transmission

   

   Heterosexual (n: 73, 72%)

19/24, 79%

54/78, 69%

0.269

   men who have sex with men (n: 24, 23%)

3/24, 12%

21/78, 27%

 

   IVDU/infected blood (n: 5, 5%)

2/24, 8%

3/78, 4%

 

HIV clinical stage

   

   AIDS (n: 43, 42%)

8/24, 33%

35/78, 45%

0.317

   non-AIDS (n: 59, 58%)

16/24, 67%

43/78, 55%

 

Hepatitis virus coinfections

   

   No (n: 93, 91%)

20/24, 83%

73/78, 94%

0.121

   Yes (n: 9, 9%)

4/24, 17%

5/78, 6%

 

Baseline CD4+ T cells/μL

   

   < 100/μL (n: 48, 47%)

8/24, 33%

40/78, 51%

0.123

   ≥ 100/μL (n: 54, 53%)

16/24, 67%

38/78, 49%

 

Baseline HIV-RNA (copies/mL, log 10 )

   

   < 5 log10/mL (n: 26, 25%)

8/24, 33%

18/78, 23%

0.313

   ≥ 5 log10/mL (n: 76, 74%

16/24, 67%

60/78, 77%

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