Inconvenience due to travelers' diarrhea: a prospective follow-up study

BMC Infectious Diseases

Table 4 Logistic regression model evaluating which symptoms best predicted incapacitation due to travelers' diarrhea.

Characteristic	All with TD n = 160	Conducted program as planned n = 107	Incapacitated n = 53	Univariate OR [95% CI]	p-value	Multivariate OR [95% CI]
Stool frequency					< 0.001
3 stools/day	76 (48)	64 (60)	12 (23)	1.0		1.0
4-5 stools/day	58 (36)	35 (33)	23 (43)	3.51 [1.56-7.88]		2.05 [0.77-5.43]
> 5 stools/day	26 (16)	8 (8)	18 (34)	12.0 [4.26-33.8]		4.84 [1.40-16.8]
Abdominal cramps					0.005
No abdominal cramps	37 (23)	32 (30)	5 (9)	1.0		1.0
1 -3 days	95 (59)	62 (58)	33 (62)	3.41 [1.21-9.57]		1.86 [0.55-6.34]
> 3 days	28 (18)	13 (12)	15 (28)	7.39 [2.22-24.5]		2.64 [0.62-11.3]
Fecal urgency ¹	114 (71)	69 (65)	45 (85)	3.10 [1.32-7.25]	0.009	0.93 [0.32-2.70]
Nausea ²	61 (38)	25 (23)	36 (68)	6.95 [3.35-14.4]	< 0.001	4.38 [1.70-11.3]
Vomiting ³	32 (20)	13 (12)	19 (36)	4.04 [1.80-9.06]	0.001	0.96 [0.32-2.91]
Fever ⁴	25 (16)	6 (6)	19 (36)	9.41 [3.47-25.5]	< 0.001	5.65 [1.80-17.7]

TD: travelers' diarrhea; OR: odds ratio; CI: confidence interval. P-values based on χ²-tests for categorical variables. Variables with p < 0.2 were included in the multivariate logistic regression model. Reference category: ¹no fecal urgency, ²no nausea, ³no vomiting, ⁴no fever. Model: constant = 0.06, Nagelkerke's R² = 0.42, Hosmer and Lemeshow test for goodness of fit p = 0.7.

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