Table 1 Demographic and clinical characteristics of patients enrolled in the study.
| Â | Sepsis | Severe sepsis/shock | p |
|---|---|---|---|
Number | 125 | 88 | Â |
Male/Female | 69/56 | 43/45 | 0.307 |
Age (years, mean ± SD) | 62.5 ± 22.2 | 72.5 ± 13.1 | < 0.0001 |
APACHE II score | 11.52 ± 5.76 | 22.68 ± 8.50 | < 0.0001 |
Type of infection (n) | Â | Â | p: 0.004 |
Acute pyelonephritis | 56 | 18 | Â |
Pneumonia (CAP) | 16 | 20 | Â |
Intra-abdominal Infection | 30 | 20 | Â |
Bacteremia | 13 | 15 | Â |
VAP/HAP | 10 | 15 | Â |
Predisposing Factors (n, %) | Â | Â | 0.188 |
Chronic Renal Disease | 15 (12.0) | 12 (13.6) | Â |
Chronic Obstructive Pulmonary Disease | 10 (8.0) | 10 (11.4) | Â |
Heart Failure | 9 (7.2) | 17 (19.3) | Â |
Diabetes mellitus type 2 | 27 (21.6) | 17 (19.3) | Â |
Solid tumor malignancy | 5 (4.0) | 7 (7.9) | Â |
Isolated pathogens irrespective of source (n, %) | Â | Â | 0.037 |
Escherichia coli | 21 (16.8) | 4 (4.5) | Â |
Pseudomonas aeruginosa | 7 (5.6) | 5 (5.7) | Â |
Klebsiella pneumoniae | 5 (4) | 9 (10.2) | Â |
Acinetobacter baumannii | 2 (1.6) | 7 (7.9) | Â |
Other Gram-negatives | 10 (8.0) | 4 (4.5) | Â |
Staphylococcus aureus | 2 (1.6) | 2 (2.3) | Â |
Other Gram-positive | 2 (1.6) | 2 (2.3) | Â |
Death | 10 (8.0) | 49 (55.7) | < 0.0001 |