Skip to main content

Table 4 Logistic Regression Results.

From: Factors associated with paradoxical immune response to antiretroviral therapy in HIV infected patients: a case control study

Characteristics Univariate analysis Multivariate analysisb
  p-value OR CI 95% p-value Aj OR CI 95%
Total time in use of HAART 0.000a - - 0.013a 0.981 0.96-0.99
Concomitant medications over 30 consecutive days in previous year 0.002a    0.109   
Yes    -    -
No   0.29 0.13-0.65   0.423 0.14-1.21
Modifications in HAART before previous year due to abandonment or poor adherence 0.018a    0.159   
No    -    -
Yes   3.39 1.33-8.65   2.852 0.66-12.25
Regimen containing zidovudine 0.021a    0.359   
Yes    -    -
No   2.28 1.11-4.66   1.601 0.58-4.37
AIDS defining illness prior to HAART 0.040a    0.515   
Yes   0.88 0.28-2.77   1.475 0.45-4.74
No    -    -
Irregular use of HAART in previous year 0.071a    0.403   
Yes   2.22 0.91-5.39   1.888 0.42-8.36
No    -    -
Nadir CD4-count 0.000a - - 0.000a 0.985 0.97-0.99
Time of undetectable HIVVL 0.000a - - 0.037a 0.969 0.94-0.99
  1. OR, odds ratio; CI 95%, confidence interval of 95%; Aj OR, adjusted odds ratio; HAART, highly active antiretroviral therapy; nadir CD4-count, the lowest CD4 ever presented by patient; HIVVL, HIV viral load; undetectable HIVVL, over time the most common limit of detection was less than 400 copies/ml.
  2. a p-value < 0,050.
  3. b Multivariate analysis was performed by the binary logistic regression model using Enter method for all variables with a p-value < 0.1 in the bivariate analysis model who fitted the requirements for logistic regression. It is important to note that the inclusion of variables in this model was performed according to a hierarchical causal theoretical tree previously developed for this study.