Delta neutrophil index as an early marker of disease severity in critically ill patients with sepsis

BMC Infectious Diseases

Table 1 Baseline clinical characteristics of patients by survival

Variables	Survivors (n = 56)	Nonsurvivors (n = 47)	p
Age	62.6 ± 17.5	69.4 ± 12.4	0.081
Gender (male)	35 (62.5%)	33 (70.2%)	0.410
Primary site of infection
Lung	26 (46.4%)	30 (63.8%)
Intra-abdomen	13 (23.2%)	11 (23.4%)
Genitourinary	13 (23.2%)	6 (12.8%)
Skin and soft tissue	3 (5.4%)	0 (0%)
Others	1 (1.8%)	0 (0%)
Severe sepsis/septic shock	17 (30.4%)	27 (57.4%)	0.005
Overt DIC	12 (21.4%)	28 (59.6%)	< 0.001
Positive blood culture	24 (42.8%)	26 (55.3%)	0.305
Gram positive	6 (10.7%)	4 (8.5%)
Gram negative	10 (17.8%)	18 (38.3%)
Fungus	8 (14.3%)	4 (8.5%)
None detected	32 (57.2%)	21 (44.7%)
SAPS 3	62.8 ± 13.6	76.5 ± 14.8	< 0.001
SOFA score	7.9 ± 4.2	11.7 ± 4.8	< 0.001
Mechanical ventilation	31 (55.4%)	29 (61.7%)	0.564
Renal replacement therapy	12 (21.4%)	24 (51.1%)	0.002
Norepinephrine infusion	1.4 ± 3.1	0.7 ± 1.3	0.107
Urine output (24 hours)	2640.7 ± 1461.6	2543.9 ± 1434.6	0.791

Continuous variables are presented as the mean ± standard deviation. Categorical variables are expressed as absolute and relative frequencies within each column.
DIC, disseminated intravascular coagulation; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; Norepinephrine infusion, average amount of norepinephrine infusion per hour during the first 24 hours in the intensive care unit (ICU); Urine output, total amount of urine output during the first 24 hours in the ICU.

ISSN: 1471-2334