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Table 3 Incidence rates of and predictors for acquiring 2nd or later TD episodes among 597 travellers in a prospective cohort from the Netherlands to developing countries, October 2006 - October 2007

From: Incidence, risk factors and treatment of diarrhoea among Dutch travellers: reasons not to routinely prescribe antibiotics

Diarrhoea

 

Subsequent episodes

Person-days of travel

Crude Incidence Rate per 100 travel days (95%CI)

Incidence Rate Ratio, univariate (95%CI)

P value

Incidence Rate Ratio, multivariate (95%CI)

P value

Total

 

184

6690

2.75 (2.38 - 3.18)

    

Sex

        
 

Male

57

2687

2.12 (1.64 - 2.75)

1.00

0.010

1.00

0.009

 

Female

127

4003

3.17 (2.67 - 3.78)

1.50 (1.09 - 2.04)

 

1.50 (1.10 - 2.05)

 

Age group, years

       
 

18-30

80

2945

2.72 (2.18 - 3.38)

1.00

0.534

1.00

0.504

 

31-45

45

1824

2.47 (1.84 - 3.30)

0.91 (0.63 - 1.31)

 

0.93 (0.65 - 1.34)

 
 

46-80

59

1921

3.07 (2,38 - 3,96)

1.13 (0.81 - 1.58)

 

1.16 (0.83 - 1.63)

 

Country of birth

       
 

Netherlands

168

6091

2.76 (2.37 - 3.21)

1.00

0.555

  
 

Other Western country

10

294

3.40 (1.83 - 6.32)

1.23 (0.65 - 2.33)

   
 

Non-Western country

6

305

1.97 (0.88 - 4.38)

0.71 (0.32 - 1.61)

   

Primary purpose of travel

       
 

Tourism

156

5649

2.76 (2.36 - 3.23)

1.00

0.658

  
 

Work or education

24

823

2.92 (1.96 - 4.35)

1.06 (0.69 - 1.62)

   
 

Visiting friends and/or relatives

4

218

1.84 (0.69 - 4.89)

0.66 (0.25 - 1.79)

   

Previous travel to a developing country

       
 

Never

25

1344

1.86 (1.26 - 2.75)

1.00

0.069

  
 

1 to 5 times

122

4082

2.99 (2.50 - 3.57)

1.61 (1.05 - 2.47)

   
 

6 times or more

37

1264

2.93 (2.12 - 4.04)

1.57 (0.95 - 2.61)

   

Travel destination

       

Latin America

South America

27

875

3.09 (2.12 - 4.50)

1.00

0.064

  
 

Central America and Caribbean

8

472

1.70 (0.85 - 3.39)

0.55 (0.25 - 1.21)

   

Africa

Southern and Eastern Africa

29

1098

2.64 (1.84 - 3.80)

0.86 (0.51 - 1.45)

   
 

Middle, Western and Northern Africa

26

532

4.89 (3.33 - 7.18)

1.58 (0.92 - 2.71)

   

Asia

South-Eastern and Eastern Asia

69

2625

2.63 (2.08 - 3.33)

0.85 (0.55 - 1.33)

   
 

South-Central and Western Asia

18

871

2.07 (1.30 - 3.28)

0.67 (0.37 - 1.22)

   

Several regions

Several regions

7

199

3.52 (1.68 - 7.38)

1.14 (0.50 - 2.62)

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