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Table 4 Laboratory parameters at admission for 5 categories of Acute Encephalitis Syndrome

From: Clinical and prognostic features among children with acute encephalitis syndrome in Nepal; a retrospective study

Laboratory parameters

Confirmed JE

AES unknown viral aetiology (n = 103)

AES bacterial aetiology (n = 39)

  

Non-JE

JE Status Unknown

Bact.

Bact. and JEV+

No. patients

42

44

59

31

8

Blood

     

Hemoglobin (g/L)

112(80-190)[37]

116(80-140)[37]

112(60-200)[55]

116(30-460)[24]

112(81-120)[7]

Total leucocyte count (x109/L)

10.9(2.46-33)[41]

9.6(1.8-25.8)[40]

12.5(4.0-9.8)[56]

9.5(1.48-110)[27]

12 (1.96- 190)[7]

Polymorphs (proportion)

0.73(0.08-0.92)[41]

0.72(0.3-0.96)[39]

0.75(0.16-0.93)[56]

0.77(0.50-0.92)[27]

0.82(0.63-0.95)[7]

Lymphocytes (proportion)

0.21(0.08-0.82)[41]

26(0.04-0.7)[39]

0.24(0.06-0.84)[54]

0.21(0.08-0.4)[27]

0.18(0.05-0.34)[7]

Blood sugar (mmol/L)

5.1(2.2-12.1)[13]

5.1(2.2-10.3)[20]

4.4(3.3-7.5)[26]

6.5(3.7-13.3)[4]

7.8(6.4-8.2)[5]

Urea (mmol/L)†

15(6.8-17.1)[5]

8.9(1.4-18.9)[10]

10.3(0.7-20.3)[10]

nr

9.6(5.3-21.4)[3]

Creatinine (μmol/L)

44.2(8.8-88)[3]

53.4(8.8-71.6)[11]

53.0(8.8-79.6)[13]

nr

64.5(35- 80)[3]

Sodium (mmol/L)

137(127-160)[12]

133(126-146)[17]

133(109-149)[20]

139(129-148)[9]

137 (134- 139)[2]

Potassium (mmol/L)

4.3(3-5)[12]

3.9(3-5)[17]

3.95(2-5)[20]

3.8(3.5-4.9)[9]

3.8 (3.6- 3.9)[2]

Cerebrospinal fluid

     

Total leucocyte count (x109/L)

0.043(0-0.6)[42]

0.041(0-0.83)[44]

0.035(0-0.54)[59]

0.14(0-1.4)[31]*

0.07 (0-0.4)[8]

Polymorphs (proportion)

0.1(0-1)[41]

0.3(0-1)[42]

0.26(0-1)[57]

0.7(0-1)[30]*

0.8(0-0.9)[8]

Lymphocytes (proportion)

0.5(0-1)[41]

0.38(0-1)[42]

0.6(0-1)[57]

0.3(0-1)[30]

0.15(0-1)[8]

Protein (g/L)

0.4(0-1.2)[39]

0.4(0-1.5)[40]

0.4(0.1-1.5)[53]

0.65(0.2-1.5)[30]*

0.1(0.04-5.8)[8]

Sugar (mmol/L)

3.3(1.4-5.7)[41]

3.3(0.9-5.6)[43]

3.3(1.7-6.1)[53]

2.1(1.1-3.8)[30]*

2.1(0.7- 3.3)[8]

  1. Median (range) or Number (%) [number of patients]. Significance of difference between groups by Fisher's Exact test or Mann-Whiney U test. *Significant (P < 0.01) difference between patients within AES of suspected viral aetiology and AES of bacterial aetiology; nr, not recorded; †normal range for urea (newborn to 16 years): 1.1-6.4 mmol/L [13].