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Table 3 Clinical features at admission for 5 categories of Acute Encephalitis Syndrome

From: Clinical and prognostic features among children with acute encephalitis syndrome in Nepal; a retrospective study

Clinical features

Confirmed JE

AES unknown viral aetiology (n = 103)

AES bacterial aetiology (n = 39)

  

Non-JE

JE Status Unknown

Bact. Inf.

Bact. and JEV+

No. patients (% AES patients (n = 184†))

42(23)

44(24)

59(32)

31(17)

8(4)

Age (years)

7(1-14)[42]

8(1-14)[44]

4.5(1-13)[56]

4.5(1-12)[31]

3.5(1-10)[8]

Number of males

16(38)[42]

16(36)[44]

16(27)[59]

11(35)[31]

8 [100][8]

Fever prior to admission

(days)

5.5(1-13)[42]

6(2-14)[44]

5(1-12)[59]

5(1-13)[30]

5 (1-16)[7]

Altered sensorium

30(71)[42]

29(69)[42]

35(60)[58]

13(43)[31]

5 [63][8]

Duration of altered sensorium (days)

2(1-5)[23]

2(1-7)[24]

1(0-5)[27]

3(1-4)[9]

1(1-1.1)[3]

Modified Glasgow coma score

12(5-15)[42]

14(4-15)[44]

14(3-15)[59]

15(4-15)[30]

12(7-15)[8]

Focal neurological deficit

13(32)[40]

7(16)[44]

4(7)[59]

2(12.5)[16]

1(33)[3]

Any seizure prior to admission

25(76)[33]

25(78)[32]

42(89)[47]

21(75)[28]

4(50)[8]

Generalised seizure prior to admission

22(96)[23]

22(92)[24]

35(92)[38]

21(95)[22]

3(38)[8]

Focal seizure prior to admission

1(4)[23]

0(0)[24]

1(3)[38]

0(0)[22]

0(0)[8]

Episodes of seizure prior to admission

2(2-12)[23]

1(1-7)[17]

2(1-9)[27]

1.5(1-7)[18]

1.2 (1-1.5)[2]

Est. duration of longest seizure (mins.)

6(3-60)[16]

6(3-60)[16]

5(4-60)[12]

5(1-5)[3]

10(10-10.2)[2]

Neck stiffness

23(62)[37]

27(66)[41]

28(52)[54]

18(58)[31]

5(63)[8]

Vomiting

23(79)[29]

24(83)[29]

29(88)[33]

18(78)[23]

3(38)[8]

Days of vomiting prior to admission

3(1-10)[18]

4(1-11)[21]

2(1-12)[25]

3.5(1-10)[12]

1.2(1-2)[5]

Weight (Kg)

15.25(1-30)[42]

20(9-70)[38]*

14(1-60)[55]

15(1-60)[29]

11(1-25)[8]

Axillary temperature (°C)

37.8(36.7-40)[40]

37.2(36.1-40)[38]

37.8(36.1-40)[52]

37.8(36.7-41.1)[29]

38.9(37.8-39.4)[7]

Pulse rate

(beats per min.)

101(52-150)[42]

100(69-160)[41]

110[78-170)[57]

100(70-160)[28]

120(72-130)[7]

Systolic BP (mmHg)

96(50-120)[17]

93(78-130)[20]

100(9-110)[14]

100(80-140)[11]

100(90-110)[3]

Dystolic BP (mmHg)

60(20-90)[17]

60(10-100)[20]

60(0-100)[15]

70(50-110)[11]

70(60-80)[3]

Respiratory rate

(breaths per min.)

30(20-80)[42]

28(16-60)[40]**

30(3-90)[55]

34(20-50)[30]

34(24-40)[7]

  1. Median (range) or Number (%) [number of patients]. Significance of difference between groups by Fisher's Exact test or Mann-Whiney U test. †Single patient with Plasmodium infection not presented. Significant difference between JE and Non-JE patients; P = 0.031*; P = 0.003**