| Confirmed JE (n = 42) | AES suspected viral aetiology (n = 145) | ||||
---|---|---|---|---|---|---|
Clinical Features at admission | Bad | Good | p-value | Bad | Good | p-value |
No. patients | 20 | 22 | Â | 45 | 100 | Â |
Age (years) | 10 (1-14) [20] | 4.5 (1-13) [22] | 0.004 | 8 (1-14) [45] | 6 (1-14) [97] | 0.005 |
Number of males | 5 (25) [20] | 11 (50) [22] | 0.121 | 13 (29) [45] | 30 (31) [98] | 1.000 |
Fever prior to admission (days)* | 7 (3-13) [20] | 5 (1-12) [22] | 0.010 | 7 (1-14) [45] | 5 (1-13) [100] | < 0.001 |
Altered sensorium | 17 (85) [20] | 13 (59) [22] | 0.091 | 39 (89) [44] | 55 (56) [98] | < 0.001 |
Duration of altered sensorium (days) | 2 (1-5) [13] | 2 (1-3) [10] | 0.839 | 2 (1-7) [30] | 1 (1-4) [43] | 0.009 |
Modified Glasgow coma score* | 11 (5-15) [20] | 14 (7-15) [22] | 0.001 | 11 (3-15) [44] | 14 (4-15) [98] | < 0.001 |
Focal neurological deficit | 9 (50) [18] | 4 (18) [22] | 0.046 | 17 (40) [43] | 7 (7) [100] | < 0.001 |
Any seizure prior to admission | 10 (77) [13] | 15 (75) [20] | 1.000 | 24 (77) [31] | 67 (83) [81] | 0.591 |
Episodes of seizure prior to admission‡ | 2 (1-12) [9] | 2 (1-4) [14] | 0.723 | 2 (1-12) [19] | 2 (1-7) [48] | 0.034 |
Neck stiffness | 14 (82) [17] | 9 (45) [20] | 0.040 | 29 (71) [41] | 49 (54) [91] | 0.086 |
Vomiting | 10 (71) [14] | 13 (87) [15] | 0.390 | 29 (81) [36] | 47 (86) [55] | 0.573 |
Days of vomiting prior to admission∆ | 3 (2-10) [8] | 3 (1-7) [9] | 0.400 | 3.5 (1-12) [26] | 2 (1-8) [37] | 0.019 |
Weight (kgs) | 19.5 (9-30) [20] | 13 (1-26) [22] | 0.017 | 19 (4-35) [45] | 15 (1-70) [90] | 0.040 |
Axillary temperature (°C) | 38.1 (36.7-40.0) [20] | 37.8 (36.7-39.4) [20] | 0.170 | 37.8 (36.1-40.0) [44] | 37.8 (36.1-40.0) [86] | 0.256 |
Pulse rate (beats per min.) | 101 (52-150) [20] | 104 (76-130) [22] | 0.905 | 106 (52-160) [44] | 110 (64-170) [96] | 0.972 |
Respiratory rate (breaths per min.) | 28 (20-50) [20] | 36 (20-80) [22] | 0.064 | 28 (3-60) [45] | 30 (16-90) [92] | 0.158 |
Death prior to discharge | 4 (20) [20] | 0 (0) [22] | --- | 8 (18) [45] | 0 (0) [100] | --- |
Neurological sequelae at discharge | 16 (80) [20] | 0 (0) [22] | Â | 37 (82) [45] | 0 (0) [100] | Â |
Treatment | Â | Â | Â | Â | Â | Â |
Phenytoin | 6 (30) [20] | 0 (0) [22] | 0.007 | 18 (40) [45] | 8 (8) [100] | < 0.001 |
Phenobarbitone | 5 (25) [20] | 3 (14) [22] | 0.445 | 10 (22) [45] | 10 (10) [100] | 0.067 |
Dexamethasone | 6 (30) [20] | 4 (18) [22] | 0.477 | 12 (27) [45] | 22 (22) [100] | 0.533 |
Mannitol | 6 (30) [20] | 2 (9) [22] | 0.123 | 19 (42) [45] | 15 (15) [100] | 0.001 |