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Table 2 Baseline characteristics of children with MDR TB

From: High prevalence of childhood multi-drug resistant tuberculosis in Johannesburg, South Africa: a cross sectional study

  Age (m) Sex TB previous TB contact Baseline Clinical HIV ART at baseline (m) CD4 # baseline CD4% baseline RNA PCR baseline Time to appropriate treatment (m) WAZ-score Drug Resistance
1 2 F No No αExprem, CLD Neg      LTFU$ -3.1 MDR
2 3.4 M No No ααExprem, CDH,CLD, ASD Neg      Died 3 days after investigation -3.9 MDR
3 3.8 M No No Well Neg      4.0 -0.5 MDR, Strep
4 5.2 M No No WHO IV Marasmus Pos 2     2.0 -1.8 MDR
5 11.9 M No No Kwashiorkor Neg      3.3 -3.0 MDR
6 18.5 M No Yes mom defaulted Kwashiorkor Neg      4.5 -2.0 MDR, Strep
7 25 M No Yes (father) WHO IV Kwashiorkor Pos No (Defaulted) 264 23.2 4.9 15 -2.3 MDR, Strep
8 29.2 F No Unk UWFA Neg      3 -3.2 MDR Strep
9 62 F no no WHO IV Pos 1 381 23.2 6.3 0.8 -3.5 MDR
10 83.7 F Yes 2001 and 2002 and 2008 ∞ U WHO IV CLD Pos 1st line 23 m. 2nd line regimen 4 m. Poor adherence 105 5.1 1.4 0.3 -3.5 MDR, EMB, Strep
11 96.7 F No Yes WHO IV Pos Yes 36 m Defaulter 9 1.1 5.1 1.3 -2.7 MDR, Strep, EMB
12 144 F Yes 2001, 2005, 2007 ^ Yes mom demised from TB 2004 WHO III Pos 11 m 1st line Poor adherence 2nd line regimen 15 months 254 32 4.1 2.5 -1.0 MDR, EMB, Strep
13 144 M No U WHO IV Pos 2 36 2.2 5.5 1.5 -2.4 MDR, Strep, Eth, EMB
Median 24        180 14.2 5.19 2.5 -2.8  
  1. α Ex-premature infant, CLD= chronic lung disease.
  2. αα CHD=Congenital diaphragmatic hernia, ASD=Atrial septum defect.
  3. $ LTFU= Lost to follow up
  4. ^ Resistant to ethambutol and isoniazid: treated with ethionamide and ciprofloxacin.
  5. ∞ Admitted to MDR-TB Hospital