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Table 2 Baseline characteristics of children with MDR TB

From: High prevalence of childhood multi-drug resistant tuberculosis in Johannesburg, South Africa: a cross sectional study

 

Age (m)

Sex

TB previous

TB contact

Baseline Clinical

HIV

ART at baseline (m)

CD4 # baseline

CD4% baseline

RNA PCR baseline

Time to appropriate treatment (m)

WAZ-score

Drug Resistance

1

2

F

No

No

αExprem, CLD

Neg

    

LTFU$

-3.1

MDR

2

3.4

M

No

No

ααExprem, CDH,CLD, ASD

Neg

    

Died 3 days after investigation

-3.9

MDR

3

3.8

M

No

No

Well

Neg

    

4.0

-0.5

MDR,

Strep

4

5.2

M

No

No

WHO IV Marasmus

Pos

2

   

2.0

-1.8

MDR

5

11.9

M

No

No

Kwashiorkor

Neg

    

3.3

-3.0

MDR

6

18.5

M

No

Yes mom defaulted

Kwashiorkor

Neg

    

4.5

-2.0

MDR,

Strep

7

25

M

No

Yes (father)

WHO IV Kwashiorkor

Pos

No (Defaulted)

264

23.2

4.9

15

-2.3

MDR,

Strep

8

29.2

F

No

Unk

UWFA

Neg

    

3

-3.2

MDR

Strep

9

62

F

no

no

WHO IV

Pos

1

381

23.2

6.3

0.8

-3.5

MDR

10

83.7

F

Yes 2001 and 2002 and 2008 ∞

U

WHO IV CLD

Pos

1st line 23 m. 2nd line regimen 4 m. Poor adherence

105

5.1

1.4

0.3

-3.5

MDR,

EMB,

Strep

11

96.7

F

No

Yes

WHO IV

Pos

Yes 36 m Defaulter

9

1.1

5.1

1.3

-2.7

MDR,

Strep,

EMB

12

144

F

Yes 2001, 2005, 2007 ^

Yes mom demised from TB 2004

WHO III

Pos

11 m 1st line Poor adherence 2nd line regimen 15 months

254

32

4.1

2.5

-1.0

MDR,

EMB,

Strep

13

144

M

No

U

WHO IV

Pos

2

36

2.2

5.5

1.5

-2.4

MDR,

Strep,

Eth,

EMB

Median

24

      

180

14.2

5.19

2.5

-2.8

 
  1. α Ex-premature infant, CLD= chronic lung disease.
  2. αα CHD=Congenital diaphragmatic hernia, ASD=Atrial septum defect.
  3. $ LTFU= Lost to follow up
  4. ^ Resistant to ethambutol and isoniazid: treated with ethionamide and ciprofloxacin.
  5. ∞ Admitted to MDR-TB Hospital