Table 2 Specificity of 24 Inno-Lia algorithms among 412 patients either HAART-naïve or exhibiting HIV-1 RNA ≥50 copies/mL despite HAART
Alg # | Definition | N recent | Specificity % |
|---|---|---|---|
Single-band algorithms | |||
2 | if sgp120 ≤ 1 then RECENT else older | 16 | 96.1 |
3 | if gp41 ≤.5 then RECENT else older | 0 | 100 |
3.1 | if gp41 ≤ 1 then RECENT else older | 0 | 100 |
3.2 | if gp41 ≤ 2 then RECENT else older | 6 | 98.5 |
4 | if p31 = 0 then RECENT else older | 25 | 93.9 |
4.1 | if p31 ≤ 0.5 then RECENT else older | 28 | 93.2 |
5 | if p24 ≤ 0 then RECENT else older | 9 | 97.8 |
6 | if p17 = 0 then RECENT else older | 33 | 92.0 |
Combined algorithms | |||
7 | if sgp120 + gp41 + p31 ≤ 4 then RECENT else older | 7 | 98.3 |
8 | if gp41 ≤ 0.5 OR (sgp120 + gp41 + p31 ≤ 4) OR (sgp120 + gp41 + p31 + p24 + p17≤ 6.5) then RECENT else older | 13 | 96.8 |
8.1 | if gp41 ≤ 0.5 OR (sgp120 + gp41 + p31 ≤ 4) OR ((sgp120 + gp41 + p31 + p24 + p17≤ 6.5) AND p31≤1) then RECENT else older | 13 | 96.8 |
9 | if sgp120 + gp41 ≤ 4 AND p31 = 0 then RECENT else older | 7 | 98.3 |
10 | if p31 = 0 AND p24 ≥ 2 then RECENT else older | 16 | 96.1 |
11 | if (sgp120 + gp41 ≤ 2.5) OR (sgp120 + gp41 + p31 + p24 + p17 ≤ 6.5) OR (p31 = 0 AND p24 ≥ 2) then RECENT else older | 23 | 94.4 |
11.1 | if (sgp120 + gp41 ≤ 2.5) OR ((sgp120 + gp41 + p31 + p24 + p17 ≤ 6.5) AND p31≤1) OR (p31 = 0 AND p24 ≥ 2) then RECENT else older | 23 | 94.4 |
12 | if (p24 ≥ 2 AND p31 = 0) OR (gp41 ≤.5) OR (sgp120 + gp41 + p31 ≤ 4 OR sgp120 + gp41 + p31 + p24 + p17 ≤ 6.5) then RECENT else older | 23 | 94.4 |
12.1 | if (p24 ≥ 2 AND p31 = 0) OR (gp41 ≤.5) OR (sgp120 + gp41 + p31 ≤ 4) OR (p31 ≤ 1 AND (sgp120 + gp41 + p31 + p24 + p17 ≤ 6.5)) then RECENT else older | 23 | 94.4 |
13 | if (sgp120 + gp41 ≤ 4 AND p31 = 0) OR (p31 = 0 AND p24 ≥ 2) then RECENT else older | 17 | 95.9 |
13.1 | if gp41 ≤ 2 OR (p31 = 0 AND p24 ≥ 2) then recent else older | 20 | 95.1 |
14 | if (sgp120 + gp41 + p31 + p24 + p17 ≤ 6.5 AND p31 ≤ 1) then RECENT else older | 8 | 98.1 |
15 | if (sgp120 ≤ 1 AND p31 ≤ 1) OR (gp41 ≤ 2 AND p31 ≤ 1) OR (p17 ≥ 2 AND p31 = 0) OR (p31 = 0 AND p24 ≥ 2) then RECENT else older | 18 | 95.6 |
16 | if (sgp120 ≤ 1 AND (p31 + p24 + p17 ≤ 2.5)) OR (gp41 ≤ 1 ) OR (p31 ≤ 0.5 AND (sgp120 + gp41+ p24 + p17 ≥ 15)) OR (p24 = 0 AND gp41 ≤ 2 ) OR (p24 ≥ 3 AND p31 = 0 ) then RECENT else older | 12 | 97.1 |
17 | if (sgp120 * gp41) ≤ 2 then RECENT else older | 4 | 99.0 |
18 | if (sgp120 * gp41 ≤ 1) OR (p24 + p31 = 0) then RECENT else older | 5 | 98.8 |