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Table 3 Associations between iron and inflammatory parameters and mortality among ART-naïve patients (n = 95) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

    Single Multiple*
  n mortality HR (95% CI) p value HR (95% CI) p value
Ferritin       
   Low-normal 31 4 1   1  
   High 64 16 1.8 (0.6-5.4) 0.29 1.3 (0.4-4.6) 0.68
sTfR       
   Normal-high 10 4 1   1  
   Low 85 16 2.2 (0.7-6.6) 0.16 1.7 (0.5-5.3) 0.38
hsCRP       
   < 50 mg/L 41 5 1   1  
   > 50 mg/L 54 15 2.2 (0.1-6.1) 0.12 2.1 (0.6-7.3) 0.24
  1. *Cox proportional hazard models adjusted for CD4 cell count (< 50, > 50 cells/mm3), age (< 29, > 29 years old), anemia (no anemia Hb > 13 g/dl for men and > 12 g/dl for women, mild Hb < 10.5 - 12.99 g/dL for men; and < 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL), and gender.
  2. Ferritin: High > 400 ng/mL for men or > 150 ng/mL for women, low-normal < 400 ng/mL for men or < 150 ng/mL for women; sTfR: Low < 1870 U/mL; normal-high > 1870 U/mL
  3. HR, Hazard ration; CI: confidence interval; hsCRP, high sensitive C-reactive protein.