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Table 1 Characteristics by age in untreated HIV-infected children.

From: Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Côte d'Ivoire, 2004-2009

 

Overall

Age < 1 year

Age 1 - 2 years

Age 2 - 5 years

Age 5 - 10 years

Age 10 - 15 years

BASELINE

N = 405

N = 64

N = 42

N = 108

N = 142

N = 49

Age, years, median (IQR)

4.5

(1.9; 7.5)

0.3

(0.01; 0.6)

1.7

(1.6; 1.8)

3.4

(2.6; 4.1)

7

(5.9; 8.5)

12.1

(11.2; 13.1)

Female, n (%)

189

(46.7)

30

(46.9)

19

(45.2)

47

(43.5)

75

(52.8)

18

(36.7)

Weight available, n (%)

383

(94.6)

59

(92.2)

37

(88.1)

100

(92.6)

138

(97.2)

49

(100.0)

Height available, n (%)

369

(91.1)

59

(92.2)

36

(85.7)

95

-88

131

(92.3)

48

(97.9)

   Weight for age z-score, median (IQR)

-2.09

(-3.45; -0.95)

- 1.94

(-3.01; -0.91)

-2.67

(-4.10; -1.60)

-1.93

(-3.36; -0.74)

-1.84

(-3.22; -0.75)

-2.58

(-4.05; -1.62)

   Height for age z-score, median (IQR)

-1,59

(-2;69; -0.76)

-

-1.34

(-1.47; -0.93)

-1.79

(-3.01; -0.74)

-1.32

(-2.44; -0.72)

-1.88

(-2.79; -1.06)

   Weight for height z-score, median (IQR)

-1,11

(-2.63; -0.21)

-

-1.33

(-1.32; -0.38)

-0.86

(-2.37; 0.06)

-1.38

(-3.57; -0.43)

-1.67

(-1.85; -1.49)

   Failure to thrive, n (%)

198

(51.7)

29

(49.2)

26

(70.3)

48

-48

63

(45.7)

32

(65.3)

CD4 count measurement available, n (%)

308

(76.1)

36

(56.3)

36

(85.7)

92

(85.2)

106

(74.6)

38

(94)

   CD4 cell %, median (IQR)

19

(14; 25.5)

18.3

(14.1; 26)

17.9

(11.7; 23.3)

20.7

(14; 26.2)

-

-

   CD4 count/μL, median (IQR)

403

(151; 665)

-

 

-

-

507.5

(234; 723)

213.5

(55; 413)

   Immunodepressed* children*, n (%)

112

(27.7)

10

(15.6)

10

(15.6)

26

(24.1)

39

(27.5)

27

(55.1)

CDC stage C, n (%)

50

(12.3)

7

(10.9)

6

(14.3)

12

(11.1)

14

(9.9)

11

(2.1)

Baseline cotrimoxazole prophylaxis n (%)

271

(66.9)

23

(35.9)

33

(78.6)

74

(68.5)

102

(71.8)

39

(67.4)

Born to known HIV-infected mothers

273

(67.4)

64

(100)

33

(78.6)

86

(76.6)

77

(54.2)

13

(26.5)

Diagnosis by PCR before 18 months

71

(19.2)

53

(82.8)

6

(14.3)

5

(4.6)

6

(4.2)

1

(2.1)

Mother deceased at inclusion, n (%)

97

(30.9)

1

(1.6)

1

(2.4)

15

(13.9)

52

(36.6)

28

(57.1)

Breastfeeding history, n (%)

191

(47.2)

40

(62.5)

19

(45.2)

43

(39.9)

67

(47.2)

22

(44.9)

History of PMTCT intervention

65

(18.1)

50

(78.1)

10

(23.8)

5

(4.6)

-

-

  1. Children followed-up by the CePReF and the MTCT-Plus programme, Abidjan, Côte d'Ivoire (January-2004-December 2009). n = 405. * Immunodeficiency according to the 2006 criteria;