Covariates | Incident Species 7 and 9 HPV Infections | |||||
---|---|---|---|---|---|---|
Crude IRR | 95% CI | P | @Adjusted IRR | 95% CI | P | |
Age (at study entry; continuous var) | 0.98 | 0.96-1.02 | 0.090 | 0.99 | 0.98-1.01 | 0.678 |
Mother seroconverted to HR-HPV | ||||||
No | Ref | |||||
Yes | 0.81 | 0.67-0.98 | 0.039 | 0.84 | 0.69-1.03 | 0.106 |
Mother seropositive to HR-HPV at baseline | ||||||
Yes | Ref | |||||
No | 1.10 | 0.85-1.42 | 0.463 | |||
Baseline oral HR-HPV DNA status | ||||||
HR-HPV- | Ref | |||||
HR-HPV+ | 0.80 | 0.54-1.19 | 0.285 | |||
Baseline PAP smear | ||||||
ASCUS+ | Ref | |||||
Negative (WNL) | 1.76 | 0.76-4.10 | 0.184 | |||
Marital Status at baseline | ||||||
Singe | Ref | |||||
Married | 1.19 | 0.77-1.81 | 0.419 | |||
Living with partner | 1.30 | 0.86-1.97 | 0.208 | |||
Divorced | 1.42 | 0.95-2.15 | 0.086 | |||
Employment status | ||||||
Employed | Ref | |||||
Student | 0.82 | 0.61-1.10 | 0.192 | |||
Unemployed | 0.90 | 0.75-1.07 | 0.257 | |||
Age at onset of sexual activity | ||||||
Below 13 years | Ref | |||||
Above 13 years | 1.15 | 1.05-1.27 | 0.003 | 1.05 | 0.93-1.17 | 0.394 |
No. of sexual partners until age of 20 yrs | ||||||
0-2 partners | Ref | |||||
3-5 partners | 0.89 | 0.76-1.05 | 0.201 | |||
6-10 partners | 1.05 | 0.92-1.19 | 0.410 | |||
> 10 partners | 0.73 | 0.46-1.18 | 0.206 | |||
Life-time number of sexual partners | ||||||
1-2 partners | Ref | |||||
3-5 partners | 1.12 | 1.02-1.24 | 0.015 | 1.12 | 1.02-1.23 | 0.011 |
6-10 partners | 0.83 | 0.61-1.13 | 0.246 | 0.85 | 0.62-1.16 | 0.311 |
> 10 partners | 0.81 | 0.63-1.04 | 0.105 | 0.81 | 0.63-1.04 | 0.104 |
No. of weekly intercourse | ||||||
0-1 intercourse | Ref | |||||
2-4 intercourses | NC | |||||
5-10 intercourses | NC | |||||
> 10 intercourses | NC | |||||
> 10 vs. 0-1 (only calculable) | 1.03 | 0.88-1.14 | 0.961 | |||
No. of deliveries in all partnerships (continuous var)* | 1.06 | 0.98-1.15 | 0.107 | |||
Practices of oral sex | ||||||
No | Ref | |||||
Yes | 1.02 | 0.87-1.20 | 0.739 | |||
Practices of anal sex | ||||||
No | Ref | |||||
Yes | 1.22 | 0.97-1.55 | 0.087 | 1.16 | 0.83-1.62 | 0.375 |
Initiation of OC usage | ||||||
Above 20 years | Ref | |||||
Below 20 years | 1.32 | 1.04-1.23 | 0.004 | 1.13 | 1.02-1.26 | 0.017 |
OC use (Y/N) | ||||||
Never use | Ref | |||||
Ever use | 1.01 | 0.74-1.37 | 0.948 | |||
Smoking habits | ||||||
Never smoker | Ref | |||||
Ever smoker | 1.06 | 0.92-1.21 | 0.384 | |||
Initiation of smoking | ||||||
10-13 years of age | ||||||
> 13 years of age | 1.16 | 1.01-1.35 | 0.028 | 1.11 | 0.95-1.31 | 0.159 |
History of STD | ||||||
Yes | Ref | |||||
No | 1.06 | 0.89-1.27 | 0.505 | |||
History of genital warts | ||||||
No | Ref | |||||
Yes | 0.93 | 0.81-1.08 | 0.372 | |||
History of oral warts | ||||||
Yes | Ref | |||||
No | 1.08 | 0.79-1.32 | 0.823 | |||
2nd pregnancy during FU | ||||||
No 2nd pregnancy during FU | Ref | |||||
Yes, 2nd pregnancy during FU | 0.29 | 0.16-0.55 | 0.0001 | 0.32 | 0.17-0.61 | 0.0001 |
Change in marital status during FU* | ||||||
No | Ref | |||||
Yes; living with partner | 0.74 | 0.41-1.32 | 0.315 | 0.78 | 0.48-1.28 | 0.340 |
Yes, married | 1.04 | 0.89-1.22 | 0.572 | 1.10 | 0.84-1.45 | 0.474 |
Yes, divorced | 1.11 | 1.01-1.22 | 0.019 | 1.16 | 0.97-1.40 | 0.102 |
No. of current sexual partners* | ||||||
No | Ref | |||||
1 or more | 1.02 | 1.00-1.04 | 0.027 | ** |