Table 2 Univariate linear regression analysis of bacterial load by known variables

M. catarrhalis

Sex

Male

180

14.26(2.89)

-0.29(-0.82 to 0.24)

0.279

Female

186

13.77(3.89)

Age category

<3mo

36

11.59(5.96)

-2.31(-3.44 to -1.18)

<0.001

3-6mo

95

14.41(2.92)

-0.45(-1.37 to 0.47)

0.336

6-9mo

122

13.85(3.51)

-0.88(-1.77 to 0.00)

0.051

9-12mo

71

14.50(1.77)

-0.47(-1.44 to -0.49)

0.335

>12mo

42

14.84(2.68)

Baselevel

--

Overall

0.001

Antibiotics

No

193

13.78(3.57)

0.42(-0.11 to 0.95)

0.123

(<2 weeks)

Yes

173

14.27(3.29)

Number of viruses

0

138

13.51(4.09)

Baselevel

--

1

153

14.08(3.42)

0.42(-0.17 to 1.01)

0.166

>1

75

14.79(1.56)

0.92(0.20 to 1.64)

0.013

Overall

0.042

H. influenzae

Sex

Male

180

12.96(4.61)

0.21(-0.38 to 0.80)

0.478

Female

186

13.24(4.48)

Age category

<3mo

36

10.26(7.10)

-1.71(-3.0 to -0.43)

0.009

3-6mo

95

13.46(4.50)

-0.01(-1.04 to 1.01)

0.981

6-9mo

122

13.23(4.29)

-0.33(-1.32 to 0.66)

0.513

9-12mo

71

13.36(3.71)

-0.32(-1.39 to 0.76)

0.565

>12mo

42

13.91(2.80)

Baselevel

--

Overall

0.041

Antibiotics

Yes

193

12.82(4.96)

0.22(-0.36 to 0.81)

0.455

(<2 weeks)

No

173

13.41(4.00)

Number of viruses

0

138

12.35(5.13)

Baselevel

--

1

153

13.34(4.35)

0.65(-0.01 to 1.30)

0.05

>1

75

13.98(3.46)

1.00(0.21 to 1.81)

0.013

Overall

0.029

S. pneumoniae

Sex

Male

180

12.22(3.96)

-0.41(-0.93 to 0.11)

0.119

Female

186

11.39(4.80)

Age category

<3mo

36

9.83(6.03)

-1.13(-2.26 to -0.02)

0.05

3-6mo

95

12.61(3.40)

0.22(-0.68 to 1.13)

0.627

6-9mo

122

11.54(4.92)

-0.20(-1.08 to 0.67)

0.647

9-12mo

71

11.89(3.84)

-0.37(-1.32 to 0.58)

0.448

>12mo

42

12.25(3.82)

Baselevel

--

Overall

0.083

Antibiotics

Yes

193

11.84(4.25)

0.05(-0.47 to 0.56)

0.862

(<2 weeks)

No

173

11.76(4.62)

Number of viruses

0

138

11.30(4.96)

Baselevel

--

1

153

12.13(3.99)

0.34(-0.24 to 0.92)

0.252

>1

75

12.04(4.19)

0.73(-0.35 to 1.07)

0.319

Overall

0.444

Total Bacterial Load

Sex

Male

180

17.46(1.65)

-0.06(-0.40 to 0.28)

0.74

Female

186

17.40(1.65)

Age category

<3mo

36

17.52(2.12)

0.27(-0.46 to 1.00)

0.464

3-6mo

95

17.71(1.44)

0.46(-0.14 to 1.06)

0.131

6-9mo

122

17.45(1.76)

0.21(-0.37 to 0.79)

0.48

9-12mo

71

17.10(1.50)

-0.15(-0.78 to 0.48)

0.646

>12mo

42

17.25(1.46)

Baselevel

--

Overall

0.185

Antibiotics

Yes

193

17.36(1.61)

0.14(-0.20 to 0.48)

0.414

(<2 weeks)

No

173

17.51(1.69)

Number of viruses

0

138

17.42(1.68)

Baselevel

--

1

153

17.42(1.70)

0.01(-0.37 to 0.39)

0.976

>1

75

17.46(1.48)

0.03(-0.44 to 0.49)

0.901

Overall

0.992