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Table 2 Univariate linear regression analysis of bacterial load by known variables

From: Viral-bacterial co-infection in Australian Indigenous children with acute otitis media

  Variables N Geometric Mean Bacterial Load (SD) Coefficient (95% CI) P
M. catarrhalis Sex Male 180 14.26(2.89) -0.29(-0.82 to 0.24) 0.279
   Female 186 13.77(3.89)   
  Age category <3mo 36 11.59(5.96) -2.31(-3.44 to -1.18) <0.001
   3-6mo 95 14.41(2.92) -0.45(-1.37 to 0.47) 0.336
   6-9mo 122 13.85(3.51) -0.88(-1.77 to 0.00) 0.051
   9-12mo 71 14.50(1.77) -0.47(-1.44 to -0.49) 0.335
   >12mo 42 14.84(2.68) Baselevel --
   Overall     0.001
  Antibiotics No 193 13.78(3.57) 0.42(-0.11 to 0.95) 0.123
  (<2 weeks) Yes 173 14.27(3.29)   
  Number of viruses 0 138 13.51(4.09) Baselevel --
   1 153 14.08(3.42) 0.42(-0.17 to 1.01) 0.166
   >1 75 14.79(1.56) 0.92(0.20 to 1.64) 0.013
   Overall     0.042
H. influenzae Sex Male 180 12.96(4.61) 0.21(-0.38 to 0.80) 0.478
   Female 186 13.24(4.48)   
  Age category <3mo 36 10.26(7.10) -1.71(-3.0 to -0.43) 0.009
   3-6mo 95 13.46(4.50) -0.01(-1.04 to 1.01) 0.981
   6-9mo 122 13.23(4.29) -0.33(-1.32 to 0.66) 0.513
   9-12mo 71 13.36(3.71) -0.32(-1.39 to 0.76) 0.565
   >12mo 42 13.91(2.80) Baselevel --
   Overall     0.041
  Antibiotics Yes 193 12.82(4.96) 0.22(-0.36 to 0.81) 0.455
  (<2 weeks) No 173 13.41(4.00)   
  Number of viruses 0 138 12.35(5.13) Baselevel --
   1 153 13.34(4.35) 0.65(-0.01 to 1.30) 0.05
   >1 75 13.98(3.46) 1.00(0.21 to 1.81) 0.013
   Overall     0.029
S. pneumoniae Sex Male 180 12.22(3.96) -0.41(-0.93 to 0.11) 0.119
   Female 186 11.39(4.80)   
  Age category <3mo 36 9.83(6.03) -1.13(-2.26 to -0.02) 0.05
   3-6mo 95 12.61(3.40) 0.22(-0.68 to 1.13) 0.627
   6-9mo 122 11.54(4.92) -0.20(-1.08 to 0.67) 0.647
   9-12mo 71 11.89(3.84) -0.37(-1.32 to 0.58) 0.448
   >12mo 42 12.25(3.82) Baselevel --
   Overall     0.083
  Antibiotics Yes 193 11.84(4.25) 0.05(-0.47 to 0.56) 0.862
  (<2 weeks) No 173 11.76(4.62)   
  Number of viruses 0 138 11.30(4.96) Baselevel --
   1 153 12.13(3.99) 0.34(-0.24 to 0.92) 0.252
   >1 75 12.04(4.19) 0.73(-0.35 to 1.07) 0.319
   Overall     0.444
Total Bacterial Load Sex Male 180 17.46(1.65) -0.06(-0.40 to 0.28) 0.74
   Female 186 17.40(1.65)   
  Age category <3mo 36 17.52(2.12) 0.27(-0.46 to 1.00) 0.464
   3-6mo 95 17.71(1.44) 0.46(-0.14 to 1.06) 0.131
   6-9mo 122 17.45(1.76) 0.21(-0.37 to 0.79) 0.48
   9-12mo 71 17.10(1.50) -0.15(-0.78 to 0.48) 0.646
   >12mo 42 17.25(1.46) Baselevel --
   Overall     0.185
  Antibiotics Yes 193 17.36(1.61) 0.14(-0.20 to 0.48) 0.414
  (<2 weeks) No 173 17.51(1.69)   
  Number of viruses 0 138 17.42(1.68) Baselevel --
   1 153 17.42(1.70) 0.01(-0.37 to 0.39) 0.976
   >1 75 17.46(1.48) 0.03(-0.44 to 0.49) 0.901
   Overall     0.992
  1. Antibiotic use included any systemic antimicrobial prescription for respiratory infection in the 2 weeks prior to examination and swabbing.