Table 4 Performance parameters of magnetic bead FM following blinded re-checking of discrepant results, compared with culture on MGIT 960 and Lowenstein-Jensen medium
| Culture (MGIT + LJ) | ||||
|---|---|---|---|---|
| Positive | Negative | Total | ||
| Magnetic bead FM (with blinded re-checking of discrepants) | ||||
| Positive | 76 | 12 | 88 | |
| Negative | 31 | 163 | 194 | |
| Total | 107 | 175 | 282 | |
|
Sensitivity, %
(95% CI) |
71.0%
(61.5 - 79.4) | |||
|
Specificity, %
(95% CI) |
93.1%
(88.3 - 96.4) | |||
|
Overall accuracy, %
(95% CI) |
84.8%
(80.0-88.7) | |||
|
PPV, %
(95% CI) |
86.4%
(77.4-92.8) | |||
|
NPV, %
(95% CI) |
84.0%
(80.0-88.7) | |||
