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Table 4 Performance parameters of magnetic bead FM following blinded re-checking of discrepant results, compared with culture on MGIT 960 and Lowenstein-Jensen medium

From: Feasibility of magnetic bead technology for concentration of mycobacteria in sputum prior to fluorescence microscopy

  

Culture (MGIT + LJ)

  

Positive

Negative

Total

Magnetic bead FM (with blinded re-checking of discrepants)

 

Positive

76

12

88

 

Negative

31

163

194

 

Total

107

175

282

Sensitivity, %

(95% CI)

71.0%

(61.5 - 79.4)

Specificity, %

(95% CI)

93.1%

(88.3 - 96.4)

Overall accuracy, %

(95% CI)

84.8%

(80.0-88.7)

PPV, %

(95% CI)

86.4%

(77.4-92.8)

NPV, %

(95% CI)

84.0%

(80.0-88.7)

  1. CI, confidence interval
  2. PPV, positive predictive value
  3. NPV, negative predictive value
  4. ZN, Ziehl-Neelsen
  5. FM, fluorescence microscopy