What zinc supplementation does and does not achieve in diarrhea prevention: a systematic review and meta-analysis

BMC Infectious Diseases

Table 3 Comparison of the results our study with those published previously

Outcome	Meta-analysis	RCTs	N	Statistic	Point Estimate	95% CI	I²(%)
Incidence of diarrhea	M1	7	1502	OR	0.82	0.72 - 0.93	---
	M2	15	6272	RR	0.86	0.79 - 0.93	77.3
	M3	24	16665	RR	0.80	0.71 - 0.90	---
	This study	31	144962	RR	0.91	0.86 - 0.95	65.5
Prevalence of diarrhea	M1	7	1502	OR	0.75	0.63 - 0.88	---
	This study	15	6534	RR	0.81	0.75 - 0.88	89.5
Incidence of persistent diarrhea	M1	6	1770	OR	0.67	0.42 - 1.06	---
	M2	3	2585	RR	0.75	0.57 - 0.98	56.3
	This study	11	68005	RR	0.89	0.73 - 1.09	25.4
Incidence of dysentery	M1	3	884	OR	0.87	0.64 - 1.19	---
	M2	4	4250	RR	0.85	0.75 - 0.95	30.3
	This study	7	72837	RR	0.89	0.75 - 1.06	37.9
Mortality	M4	4	86152	RR	0.91	0.82 - 1.02	---
	M3	10	201616	RR	0.94	0.86 - 1.02	---
	This study	12	229930	RR	0.90	0.78 - 1.04	48.1

---, not reported
M1, Bhutta et al 1999[5]; M2, Aggarwal et al 2007[4]; M3, Brown et al 2009[6]; M4, Tielsch et al 2007[45]
OR, odds ratio; RR, relative risk; RCT, randomized controlled trial; CI, confidence interval

ISSN: 1471-2334