Performance of whole-blood interferon-gamma release assay in patients admitted to the emergency department with pulmonary infiltrates

Table 3 Univariate and multivariate analysis of factors associated with indeterminate QuantiFERON results in inpatients with pulmonary infiltrates

Covariate	Determinate (n = 200)	indeterminate (n = 84)	Univariate		Multivariate
			Odds ratio	95% confidence interval	Odds ratio	95% confidence interval
Age, yr	62 ± 17.1	67 ± 14.5	1.018	1.001-1.035
Lymphocytes cells/μL	1170 ± 935	764 ± 451	0.999	0.998-0.999
Lymphocytopenia*
Absence	99 (49.5)	19 (22.6)	1.0		1.0
Presence	101 (50.5)	65 (77.4)	3.353	1.875-5.998	2.688	1.424-5.075
Albumin, g/dL	3.4 ± 0.60	3.0 ± 0.54	0.307	0.190-0.495	0.412	0.245-0.694
ESR, mm/hr	58.3 ± 35.88	67.2 ± 32.52	1.007	1.000-1.015
CRP, mg/dL	9.2 ± 8.43	15.7 ± 9.65	1.078	1.046-1.110	1.060	1.027-1.094

Data are shown as mean ± SD or No. (%).
ESR, erythrocyte sedimentation rate; CRP, C-reactive protein.
QuantiFERON test was performed by using QuantiFERON^®- TB Gold or QuantiFERON ^®- TB Gold In-Tube.
* Lymphocytopenia; < 1,000 cells/μL.

ISSN: 1471-2334