Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life

Table 1 Anti-HBs antibody responses before and one month after challenge dose (ATP Cohort for immunogenicity)

		Seropositivity/Seroprotection rates
		≥ 3.3 mIU/mL			≥ 10 mIU/mL			≥ 100 mIU/mL			GMC
Time point	N	n	%	[95% CI]	n	%	[95% CI]	n	%	[95% CI]	Value	[95% CI]
Pre	285	264	92.6	[89.0; 95.4]	243	85.3	[80.6; 89.2]	134	47.0	[41.1; 53.0]	83.7	[66.8; 104.9]
Post	286	284	99.3	[97.5; 99.9]	282	98.6	[96.5; 99.6]	274	95.8	[92.8; 97.8]	8656.1	[6560.7; 11420.9]

GMC = geometric mean antibody concentration. N = number of subjects with available results. n/% = number/percentage of subjects with antibody concentrations above the specified cut-off. 95% CI = exact 95% confidence interval. Pre = prior to the administration of challenge dose, Post = one month after the challenge dose

ISSN: 1471-2334