Skip to main content

Advertisement

Table 4 Results of neutralization test with poliovirus type 1 strain CHAT and Poliovirus Type 1 Strain Sabin (LSc-2ab) in three different laboratories.

From: Immunity status of adults and children against poliomyelitis virus type 1 strains CHAT and Sabin (LSc-2ab) in Germany

  Laboratory Nr. 1 Laboratory Nr. 2 Laboratory Nr. 3
Case
No.
CHAT
ATTC
VR-1562
Sabin 1
WHO reference strain
Ratio* CHAT
ATTC
VR-1562
Sabin 1
WHO reference strain
Ratio CHAT
ATTC
VR-1562
Sabin 1
WHO reference strain
Ratio
  GMT** (IU/ml) GMT (IU/ml)   GMT IU/ml GMT IU/ml   GMT IU/ml GMT IU/ml  
7b < 8 (< 1,1) 91 (4,9) > 4,5 12 (0,6) 192 (4,1) 7,1 < 10 (< 1,3) 80 (5,3) > 4,1
9 8 (1,1) 64 (3,4) 3,1 32 (1,5) 128 (2,7) 1,8 < 10 (< 1,3) 40 (2,7) > 2,0
12b 23 (3,2) 362 (19,5) 6,1 64 (3,1) 256 (5,5) 1,8 10 (2,6) 160 (10,6) 4,1
13b 32 (4,4) > 786 (> 42,3) > 9,4 48 (2,3) > 512 (> 11) > 4,7 20 (5,2) 640 (42,4) 8,2
28b 32 (4,4) 64 (3,4) 0,8 96 (4,6) 128 (2,7) 0,6 20 (5,2) 40 (2,7) 0,5
16b 64 (8,9) 512 (27,5) 3,1 128 (6,2) 512 (11,0) 1,8 20 (5,2) 320 (21,2) 4,1
21 128 17,8 2048 110,1 6,2 384 (18,6) > 512 (> 11) > 0,6 40 (10,4) 1280 (84,8) 8,2
8b 256 (35,6) 362 (19,5) 0,5 512 (24,8) 512 (11,0) 0,4 80 (20,7) 320 (21,2) 1,0
34b 256 (35,6) > 786 (> 42,3) > 1,9 > 512 (> 25) > 512 (> 11) - 80 (20,7) 320 (21,2) 1,0
Internal control 41 (5,7) 106 (5,7) 1,0 62 (3) 140 (3) 1,0 22 (5,7) 86 (5,7) 1,0
  1. Laboratory Nr. 1 - Labor Enders, Stuttgart, Laboratory Nr. 2 - Robert Koch-Institute (RKI), Berlin, Laboratory Nr. 3 - Institute for Medical Virology, Johann Wolfgang Goethe-University of Frankfurt
  2. *Ratio of IU/ml Sabin to IU/ml CHAT
  3. **GMT Reciprocal geometric mean titers