Table 1 Hospitalized adult patients with 2009 Influenza A (H1N1) in Beijing: demographics, comorbidities, and clinical presentation
Survivor (n = 128) | Nonsurvivor (n = 27) | Total (n = 155) | P value | |
|---|---|---|---|---|
Male sex | 73 (57.0%) | 17 (63.0%) | 90 (58.1%) | 0.570 |
Age, year | 42.4 ± 18.2 | 45.9 ± 20.7 | 43.0 ± 18.6 | 0.388 |
Ethnicity | ||||
Han Chinese | 127 (99.2%) | 25 (92.6%) | 152 (98.1%) | 0.079 |
Smoker | 28 (21.9%) | 7 (25.9%) | 35 (22.6%) | 0.647 |
No comorbidity | 60 (46.9%) | 14 (51.9%) | 74 (47.7%) | 0.609 |
Comorbidity | ||||
Cardiovascular disease | 34 (26.6%) | 11 (40.7%) | 45 (29.0%) | 0.140 |
Hypertension | 25 (19.5%) | 10 (37.0%) | 35 (22.6%) | 0.048 |
Ischemic heart disease | 19 (14.9%) | 5 (18.5%) | 24 (15.5%) | 0.572 |
Chronic lung disease | 19 (14.9%) | 3 (11.1%) | 22 (14.2%) | 0.768 |
COPD | 8 (6.3%) | 2 (7.4%) | 10 (6.5%) | 0.686 |
Diabetes | 13 (10.2%) | 7 (25.9%) | 20 (12.9%) | 0.051 |
Pregnancy or postpartum | 12 (9.4%) | 2 (7.4%) | 14 (9.0%) | 1.000 |
Pregnancy | 11 (8.6%) | 1 (3.7%) | 12 (7.7%) | 0.693 |
Postpartum < 1 month | 1 (0.8%) | 1 (3.7%) | 2 (1.3%) | 0.319 |
Cerebral vascular disease | 6 (4.7%) | 3 (11.1%) | 9 (5.8%) | 0.191 |
Symptoms at disease onset | ||||
Fever (> 37.8°C) | 121 (94.5%) | 24 (88.9%) | 145 (93.5%) | 0.380 |
Cough | 117 (91.4%) | 25 (92.6%) | 142 (91.6%) | 1.000 |
Dyspnea | 56 (43.8%) | 17 (63.0%) | 73 (47.1%) | 0.069 |
Sore throat | 42 (32.8%) | 4 (14.8%) | 46 (29.7%) | 0.063 |
Myalgia | 24 (18.8%) | 3 (11.1%) | 27 (17.4%) | 0.416 |
Rhinorrhea | 21 (16.4%) | 3 (11.1%) | 24 (15.5%) | 0.770 |
Hemoptysis | 15 (11.7%) | 4 (14.8%) | 19 (12.3%) | 0.746 |
Diarrhea | 6 (4.7%) | 1 (3.7%) | 7 (4.5%) | 1.000 |
Vomiting | 5 (3.9%) | 0 | 5 (3.2%) | 0.588 |
Time from symptoms to hospital admission, day* | 5.0 (3.0, 7.0) | 6.0 (3.5, 7.0) | 5.0 (3.0, 7.0) | 0.376 |
Clinical presentation on admission | ||||
Dyspnea | 61 (47.7%) | 21 (77.8%) | 82 (52.9%) | 0.004 |
Pneumonia on CXR | 104 (81.3%) | 25 (92.6%) | 129 (83.2%) | 0.254 |
Laboratory tests on admission | ||||
White cell count, 109/L | 6.1 ± 3.7 | 7.3 ± 5.1 | 6.3 ± 4.0 | 0.183 |
Lymphocyte, 109/L | 1.2 ± 1.4 | 0.7 ± 0.3 | 1.1 ± 1.3 | 0.118 |
CPK, U/L | 339 ± 620 | 538 ± 548 | 373 ± 610 | 0.222 |
CK-MB, μg/L | 23 ± 33 | 29 ± 22 | 24 ± 31 | 0.457 |
cTnI, μg/L | 0.16 ± 0.23 | 0.32 ± 0.69 | 0.21 ± 0.43 | 0.417 |
LDH, U/L | 356 ± 240 | 744 ± 759 | 432 ± 422 | 0.041 |
Total bilirubin, μmol/L | 20.2 ± 57.8 | 48.8 ± 156.6 | 25.8 ± 86.2 | 0.431 |
AST, U/L | 57 ± 49 | 348 ± 803 | 113 ± 366 | 0.105 |
ALT, U/L | 51 ± 111 | 123 ± 254 | 65 ± 152 | 0.209 |