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Table 1 Simple non-invasive models for liver fibrosis consisting of routine parameters.

From: Can serum hyaluronic acid replace simple non-invasive indexes to predict liver fibrosis in HIV/Hepatitis C coinfected patients?

Index Mathematical formula Reference
Forns 7.811 - 3.131 * LN(Platelet count (109/L) + 0.781 * LN(GGT) + 3.467 * LN (Age)
                       -0.014*cholesterol
[11]
APRI 100 * ( A S T ( I U / L ) 40 ) Platelet count ( 10 9 / L ) [12]
FIB-4 A g e ( y e a r s ) * A S T ( I U / L ) P l a t e l e t c o u n t ( 10 9 / L ) * A L T ( I U / L ) [13]
HGM-1 1 1 + e ( 1.971 + 0.012 * P l a t e l e t c o u n t ( 10 9 / L ) 0.026 * AST (IU/L)– 0.033 * glucose(mg/dL) ) [14]
HGM-2 1 1 + e ( 6.175 0.010 ALP ( I U / L ) 4.8 * INR + 0.010 * P l a t e l e t c o u n t ( 10 9 / L ) 0.007 * AST ( I U / L ) ) [14]
  1. Abreviations: LN, logarithm neperian; GGT, gamma glutamyl transpeptidase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; INR, international normalized ratio; ALP, alkaline phosphatase.