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Table 4 Summary of prognostic factors.

From: Predicting sequelae and death after bacterial meningitis in childhood: A systematic review of prognostic studies

Prognostic factor Moderate/high quality studies with multivariate analysis Moderate/high quality studies with univariate analysis Low quality studies with multivariate analysis Low quality studies with univariate analysis
  Hearing loss Mortality Neurological sequelae Poor outcome Hearing loss Mortality Neurological sequelae Poor outcome All outcomes All outcomes
History of symptoms >48 h 1x    1x      1x  
Coma/impaired consciousness   2x 2x 2x 1x 4x 1x 3x 1x 6x
Seizures   1x 2x 2x   2x 1x 2x 2x 4x
Shock/hypotension       3x 1x 2x   3x
Peripheral circulatory failure   1x   1x   1x     1x
Severe respiratory distress   1x     1x     1x
Prolonged fever (>7 days)    1x     1x 1x   
Seizures >12 h after admission       1x   2x 1x  
Low peripheral WBC count     2x 1x 3x 1x 2x 2x 3x
Low CSF WBC count    1x 1x   1x 1x 1x 2x 3x
Low CSF glucose level 2x    1x   1x 1x 1x 2x 6x
High CSF protein level   1x   1x 1x 2x   1x   4x
S. pneumonia as causative pathogen 2x   2x 1x       
Young age       1x 1x 2x 1x 1x
<1 years       1x   1x 1x 1x
<2 years        1x 1x   
Male gender 1x   1x 1x      2x  
Fever >40°C    1x    1x     
Absence of petechiae 1x   1x       1x