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Table 4 Summary of prognostic factors.

From: Predicting sequelae and death after bacterial meningitis in childhood: A systematic review of prognostic studies

Prognostic factor

Moderate/high quality studies with multivariate analysis

Moderate/high quality studies with univariate analysis

Low quality studies with multivariate analysis

Low quality studies with univariate analysis

 

Hearing loss

Mortality

Neurological sequelae

Poor outcome

Hearing loss

Mortality

Neurological sequelae

Poor outcome

All outcomes

All outcomes

History of symptoms >48 h

1x

  

1x

    

1x

 

Coma/impaired consciousness

 

2x

2x

2x

1x

4x

1x

3x

1x

6x

Seizures

 

1x

2x

2x

 

2x

1x

2x

2x

4x

Shock/hypotension

     

3x

1x

2x

 

3x

Peripheral circulatory failure

 

1x

 

1x

 

1x

   

1x

Severe respiratory distress

 

1x

   

1x

   

1x

Prolonged fever (>7 days)

  

1x

   

1x

1x

  

Seizures >12 h after admission

     

1x

 

2x

1x

 

Low peripheral WBC count

   

2x

1x

3x

1x

2x

2x

3x

Low CSF WBC count

  

1x

1x

 

1x

1x

1x

2x

3x

Low CSF glucose level

2x

  

1x

 

1x

1x

1x

2x

6x

High CSF protein level

 

1x

 

1x

1x

2x

 

1x

 

4x

S. pneumonia as causative pathogen

2x

 

2x

1x

      

Young age

     

1x

1x

2x

1x

1x

<1 years

     

1x

 

1x

1x

1x

<2 years

      

1x

1x

  

Male gender

1x

 

1x

1x

    

2x

 

Fever >40°C

  

1x

  

1x

    

Absence of petechiae

1x

 

1x

     

1x