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Table 2 Multivariate logistic regressions for liver and spleen pathology as assessed by clinical examination at baseline (n = 2128)

From: The impact of single versus mixed schistosome species infections on liver, spleen and bladder morbidity within Malian children pre- and post-praziquantel treatment

Estimates from multilevel logistic regressions

 

Adjusted ORs for gender and age (95% CI) and p-values for the risk of having hepatomegaly as assessed by MSL >2 cm

Type of schistosomiasis infection intensity related variables

For S. mansoni

For S. haematobium

none

light

medium

heavy

None

1

1.431

2.049

2.932

  

(1.008 to 2.033)

(1.016 to 4.132)

(1.024 to 8.399)

  

p = 0.045

p = 0.045

p = 0.045

Light

0.995

1.425

2.039

2.919

 

(0.614 to 1.612)

(0.839 to 2.419)

(0.956 to 4.349)

(1.016 to 8.383)

 

p = 0.985

p = 0.190

p = 0.065

p = 0.047

Heavy

0.991

1.418

2.03

2.905

 

(0.377 to 2.600)

(0.548 to 3.667)

(0.704 to 5.850)

(0.825 to 10.230)

 

p = 0.985

p = 0.471

p = 0.190

p = 0.097

 

Adjusted ORs for gender and age (95% CI) and p-values for the risk of having hepatomegaly as assessed by MCL>2 cm

 

For S. mansoni

For S. haematobium

none

light

medium

heavy

None

1

1.446

2.092

3.025

  

(1.006 to 2.078)

(1.013 to 4.320)

(1.019 to 8.979)

  

p = 0.046

p = 0.046

p = 0.046

Light

1.057

1.529

2.211

3.198

 

(0.652 to 1.713)

(0.895 to 2.611)

(1.017 to 4.805)

(1.078 to 9.484)

 

p = 0.822

p = 0.120

p = 0.045

p = 0.036

Heavy

1.117

1.616

2.337

3.38

 

(0.425 to 2.934)

(0.623 to 4.189)

(0.801 to 6.815)

(0.937 to 12.196)

 

p = 0.822

p = 0.323

p = 0.120

p = 0.063

 

Adjusted ORs for gender and age (95% CI) and p-values for the risk of having splenomegaly as assessed by MCL>2 cm

 

For S. mansoni

For S. haematobium

none

light

medium

heavy

None

1

1.068

1.142

1.22

  

(0.864 to 1.321)

(0.747 to 1.745)

(0.645 to 2.306)

  

p = 0.541

p = 0.541

p = 0.541

Light

0.768

0.82

0.876

0.936

 

(0.594 to 0.992)

(0.607 to 1.108)

(0.557 to 1.378)

(0.494 to 1.776)

 

p = 0.044

p = 0.197

p = 0.568

p = 0.840

Heavy

0.589

0.629

0.673

0.719

 

(0.352 to 0.985)

(0.375 to 1.057)

(0.368 to 1.228)

(0.343 to 1.505)

 

p = 0.044

p = 0.080

p = 0.197

p = 0.381

 

Adjusted ORs for gender and age (95% CI) and p-values for the risk of having splenomegaly as assessed by MAL>2 cm

 

For S. mansoni

For S. haematobium

none

light

medium

heavy

None

1

1.099

1.207

1.326

  

(0.879 to 1.373)

(0.773 to 1.886)

(0.679 to 2.591)

  

p = 0.408

p = 0.408

p = 0.408

Light

0.754

0.829

0.911

1.001

 

(0.576 to 0.988)

(0.604 to 1.139)

(0.565 to 1.468)

(0.510 to 1.965)

 

p = 0.041

p = 0.247

p = 0.701

p = 0.998

heavy

0.569

0.625

0.687

0.755

 

(0.332 to 0.977)

(0.362 to 1.079)

(0.364 to 1.296)

(0.346 to 1.646)

 

p = 0.041

p = 0.092

p = 0.247

p = 0.480

  1. ORs, Odds Ratios; 95% CIs, 95% Confidence Intervals