Incidence and determinants of new AIDS-defining illnesses after HAART initiation in a Senegalese cohort

BMC Infectious Diseases

Table 3 Rate ratio relative to the occurrence of AIDS-defining illnesses 42 months after HAART initiation (Adult Senegalese cohort, 1998-2008, 293 patients).

	Univariate analysis		Multivariate analysis
Factors	Rate ratio	95% CI	Rate ratio	95% CI
Age (year)	1.00	[0.96;1.05]
Sex (female vs. male)	0.52	[0.25; 1.07]
Baseline CD4^a	0.95	[0.82;1.10]
Baseline BMI^b (kg/m²)	0.90	[0.80; 1.01]
CDC stage at baseline (C vs. A or B)	1.77	[0.77;4.09]
VL^c ≤ 10³ cp/mL at period start	0.33	[0.15;0.73]
Current CD4 cell count^a	0.80	[0.74;0.87]	0.79	[0.71;0.87]
Variability in CD4 increase^d	0.61	[0.44;0.84]
Current viral load (≤ 10³ vs. > 10³ cp/mL)	4.33	[1.86;10.08]	2.74	[1.15;6.57]
Duration of VL^c ≤ 10³ cp/mL	0.88	[0.81; 0.96]

a: per 50 cells/mm³; b: Body Mass Index; c: Viral Load; d: per standard deviation unit.

ISSN: 1471-2334