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Table 3 Bactericidal cumulative fractions of response (CFRs) for antibiotic dosage regimens against Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa and Acinetobacter baumannii collected from Shenyang in China

From: Pharmacokinetic-pharmacodynamic profiling of four antimicrobials against Gram-negative bacteria collected from Shenyang, China

Regimen Bactericidal CFR (%)
  E. coli K. pneumoniae E. cloacae P. aeruginosa A. baumannii
Meropenem 0.5 g q6h 100 100 100 52 59
Meropenem 0.5 g q8h 100 100 97 46 59
Meropenem 1 g q8h 100 100 100 54 59
Imipenem 0.5 g q6h 100 99 97 45 36
Imipenem 0.5 g q8h 100 97 97 36 34
Imipenem 1 g q8h 100 99 98 49 37
Cefepime 1 g q8h 90 73 68 48 22
Cefepime 2 g q8h 95 83 78 68 37
Cefepime 2 g q12h 90 74 68 45 22
Piperacillin/tazobactam 4.5 g q8h 71 33 34 11 8
Levofloxacin 0.5 g every 24 h 30 44 68 33 19