Table 2 The clinical and laboratory variables in patients with Puumala hantavirus infection divided into four groups according to maximum plasma interleukin-6 and C-reactive protein levels.
Group 1 (N = 37) CRP ≤ 69 mg/l IL-6 ≤ 14.05 pg/ml | Group 2 (N = 22) CRP > 69 mg/l IL-6 ≤ 14.05 pg/ml | Group 3 (N = 23) CRP ≤ 69 mg/l IL-6 > 14.05 pg/ml | Group 4 (N = 36) CRP > 69 mg/l IL-6 > 14.05 pg/ml | P-value | |
|---|---|---|---|---|---|
Age (years) | 38 (17-63) | 51 (26-71) | 36 (15-64) | 45 (25-65) | 0.013 |
Hospital stay (days) | 6 (2-15) | 6 (3-10) | 7 (4-13) | 8 (3-14) | 0.003 |
SBP min (mmHg) | 117 (82-162) | 112 (93-149) | 110 (85-140) | 112 (86-158) | 0.092 |
Change in weight (kg) | 2.1 (0-9.9) | 1.3 (0-4.7) | 2.8 (0-12.0) | 3.3 (0-9.9) | 0.023 |
Urinary output min (ml/day) | 2230 (350-7000) | 2050 (200-4940) | 1040 (50-4900) | 1045 (50-3325) | < 0.001 |
Urinary protein max (g/day) | 1.43 (0.14-5.59) | 2.03 (0.57-4.31) | 6.05 (0.30-10.00) | 1.72 (0.30-17.78) | 0.003 |
Creatinine max (μmol/l) | 193 (65-917) | 114 (68-878) | 256 (88-1285) | 230 (70-1156) | 0.073 |
Platelets min (109/l) | 80 (3-238) | 84 (19-159) | 59 (9-139) | 54 (13-187) | 0.001 |
Hematocrit min | 0.38 (0.29-0.43) | 0.38 (0.29-0.44) | 0.34 (0.25-0.43) | 0.35 (0.25-0.46) | 0.007 |
Leukocytes max (109/l) | 9.0 (3.9-31.2) | 9.2 (5.4-18.6) | 11.0 (5.1-23.2) | 12.2 (7.1-26.8) | 0.011 |